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Macrophage Inflammatory Protein 5 Active Protein | CXCL3 active protein

Macrophage Inflammatory Protein 5, Recombinant, Human (MIP-5, Lkn-1)

Purity
Molecular Biology Grade
98% by SDS-PAGE and HPLC.
Synonyms
Macrophage Inflammatory Protein 5; Recombinant; Human (MIP-5; Lkn-1); CXCL3 active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Molecular Biology Grade
98% by SDS-PAGE and HPLC.
Form/Format
The sterile filtered solution was lyophilized with no additives.
Biological Activity
Determined by its ability to chemoattract human T lymphocytes using a concentration range of 1.0-10.0ng/ml.
Country of Origin
USA
Endotoxin Level
0.1ng/ug (1EU/ug).
Reconstitution
We recommend a quick spin followed by reconsitution in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 degree C for 1 week or -20 degree C for future use.
Preparation and Storage
-20 degree C
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored -20 degree C. Reconstituted MIP-5 should be stored in working aliquots at -20 degree C.
Product Categories/Family for CXCL3 active protein

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
11,342 Da
NCBI Official Full Name
Macrophage inflammatory protein 2-beta
UniProt Protein Name
C-X-C motif chemokine 3
Protein Family
UniProt Gene Name
CXCL3
UniProt Synonym Gene Names
GRO3; GROG; SCYB3; GRO-gamma; MIP2-beta
UniProt Entry Name
CXCL3_HUMAN

Uniprot Description

Function: Ligand for CXCR2

By similarity. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Ref.7

Subcellular location: Secreted.

Post-translational modification: N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.

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Product Notes

The Macrophage Inflammatory Protein 5 cxcl3 (Catalog #AAA650597) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Macrophage Inflammatory Protein 5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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