SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Mer recombinant protein
Recombinant Mer
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
NCBI and Uniprot Product Information
Uniprot Description
Mer: a proto-oncogene receptor tyrosine-protein kinase of the Axl family. Binds several ligands including LGALS3, Tubby, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3
Protein type: EC 2.7.10.1; Protein kinase, tyrosine (receptor); Protein kinase, TK; Oncoprotein; Membrane protein, integral; Kinase, protein; TK group; Axl family
Cellular Component: extracellular space; photoreceptor outer segment; membrane; cell; cytoplasm; integral to membrane; intracellular
Molecular Function: transferase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; transmembrane receptor protein tyrosine kinase activity; ATP binding; protein kinase activity
Biological Process: negative regulation of lymphocyte activation; platelet activation; vagina development; protein amino acid phosphorylation; phagocytosis; natural killer cell differentiation; retina development in camera-type eye; positive regulation of phagocytosis; protein kinase B signaling cascade; spermatogenesis; phosphorylation; apoptotic cell clearance; secretion by cell
Research Articles on Mer
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Product Notes
The Mer mertk (Catalog #AAA201171) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-497aa. AAA Biotech's Mer can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the Mer mertk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: GGTAEKWEET ELDQLFSGPL PGRLPVNHRP FSAPHSSRDQ LPPPQTGRSH PAHTAAPQVT STASKLLPPV AFNHTIGHIV LSEHKNVKFN CSINIPNTYQ ETAGISWWKD GKELLGAHHS ITQFYPDEEG VSIIALFSIA SVQRSDNGSY FCKMKVNNRE IVSDPIYVEV QGLPYFIKQP ESVNVTRNTA FNLTCQAVGP PEPVNIFWVQ NSSRVNEKPE RSPSVLTVPG LTETAVFSCE AHNDKGLTVS KGVHINIKVI PSPPTEVHIL NSTAHSILVS WVPGFDGYSP LQNCSIQVKE ADRLSNGSVM VFNTSASPHL YEIQQLQALA NYSIAVSCRN EIGWSAVSPW ILASTTEGAP SVAPLNITVF LNESNNILDI RWTKPPIKRQ DGELVGYRIS HVWESAGTYK ELSEEVSQNG SWAQIPVQIH NATCTVRIAA ITKGGIGPFS EPVNIIIPEH SKVDYAPSST PAPGNTDSM< L EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH>. It is sometimes possible for the material contained within the vial of "Mer, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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