Lymphotactin Active Protein | XCL1 active protein

Lymphotactin, Recombinant, Human (Small Inducible Cytokine Subfamily C Member 1, SCYC1, Chemokine C Motif Ligand 1, Ltn)

Cat. Num. AAA650359

• Gene Names: XCL1; LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
• Purity: Molecular Biology Grade; > 98% by SDS-PAGE and HPLC analyses.
• Synonyms: Lymphotactin; Recombinant; Human (Small Inducible Cytokine Subfamily C Member 1; SCYC1; Chemokine C Motif Ligand 1; Ltn); XCL1 active protein

• Host: E Coli
• Purity/Purification: Molecular Biology Grade; > 98% by SDS-PAGE and HPLC analyses.
• Form/Format: Lyophilized protein with no additives. The protein may appear as a haze or film which is difficult to see at the bottom of the vial.

• Biological Activity: Determined by its ability to chemoattract human peripheral blood lymphocytes using a concentration range of 10-100ng/ml
• Country of Origin: USA
• Endotoxin Level: < 0.1ng per ug of lymphotactin.
• Reconstitution: We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers.
• Preparation and Storage: The lyophilized protein is stable for a few weeks at RT. It is best stored at -20 degree C. Reconstituted lymphotactin should be stored in working aliquots at -20 degree C.

Related Product Information for XCL1 active protein

Lymphotactin is a newly discovered chemokine that exhibits chemotactic activity toward lymphocytes but not towards monocytes or neutrophils. Human lymphotactin is 10.2kD protein containing 92 amino acid residues.

Product Categories/Family for XCL1 active protein

Growth Factors; Cytokines; Growth Factors-Lymphotactin

NCBI and Uniprot Product Information

• NCBI GI #: 4506853
• NCBI GeneID: 6375
• NCBI Accession #: NP_002986.1
• NCBI GenBank Nucleotide #: NM_002995.2
• UniProt Accession #: P47992; Q52MA8
• Molecular Weight: 10.2kD
• NCBI Official Full Name: lymphotactin
• NCBI Official Synonym Full Names: chemokine (C motif) ligand 1
• NCBI Official Symbol: XCL1
• NCBI Official Synonym Symbols: LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
• NCBI Protein Information: lymphotactin; SCM-1-alpha; lymphotaxin; cytokine SCM-1; OTTHUMP00000032498; c motif chemokine 1; XC chemokine ligand 1; single cysteine motif 1a; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin)
• UniProt Protein Name: Lymphotactin
• Protein Family: Lymphotactin
• UniProt Gene Name: XCL1
• UniProt Synonym Gene Names: LTN; SCYC1
• UniProt Entry Name: XCL1_HUMAN

NCBI Description

This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq]

Uniprot Description

Function: Chemotactic activity for lymphocytes but not for monocytes or neutrophils.

Subcellular location: Secreted.

Tissue specificity: Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.

Sequence similarities: Belongs to the intercrine gamma family.