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Rabbit anti-Rat NERP-2 Polyclonal Antibody | anti-VGF antibody

NERP-2 (Neuroendocrine Regulatory Peptide-2, NERP2)

Reactivity
Rat
Applications
Immunohistochemistry
Purity
Serum
Serum
Synonyms
NERP-2; Polyclonal Antibody; NERP-2 (Neuroendocrine Regulatory Peptide-2; NERP2); Anti -NERP-2 (Neuroendocrine Regulatory Peptide-2; anti-VGF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat NERP-2.
Purity/Purification
Serum
Serum
Form/Format
Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
Applicable Applications for anti-VGF antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Immunogen
Synthetic peptide corresponding to rat NERP-2.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Product Categories/Family for anti-VGF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,258 Da
NCBI Official Full Name
neurosecretory protein VGF
NCBI Official Synonym Full Names
VGF nerve growth factor inducible
NCBI Official Symbol
VGF
NCBI Protein Information
neurosecretory protein VGF; neuro-endocrine specific protein VGF
UniProt Protein Name
Neurosecretory protein VGF
Protein Family
UniProt Gene Name
VGF
UniProt Synonym Gene Names
NERP-1; NERP-2
UniProt Entry Name
VGF_HUMAN

NCBI Description

This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system

By similarity. Ref.5 Ref.6NERP peptides are involved in the control of body fluid homeostasis by regulating vasopressin release. Ref.5 Ref.6Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris. Ref.5 Ref.6

Subcellular location: Secreted. Cytoplasmic vesicle › secretory vesicle. Note: Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus. Ref.6

Tissue specificity: Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells. Ref.6

Post-translational modification: Multiple peptides are derived from VGF, with activities in synaptic plasticity, antidepression, penile erection, autonomic activation, and increases in energy expenditure

By similarity.

Research Articles on VGF

Similar Products

Product Notes

The VGF vgf (Catalog #AAA646577) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NERP-2 (Neuroendocrine Regulatory Peptide-2, NERP2) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NERP-2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Researchers should empirically determine the suitability of the VGF vgf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NERP-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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