Rabbit anti-Human FCGR3B Polyclonal Antibody | anti-FCGR3B antibody
FCGR3B (Low affinity immunoglobulin gamma Fc Region Receptor III-B, Fc-gamma RIII-beta, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, FcR-10, IgG Fc Receptor III-1, CD16b, FCGR3B, CD16B, FCG3, FCGR3, IGFR3) (APC)
Gene Names
FCGR3B; CD16; FCG3; CD16A; CD16b; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
FCGR3B; Polyclonal Antibody; FCGR3B (Low affinity immunoglobulin gamma Fc Region Receptor III-B; Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc Receptor III-1; CD16b; CD16B; FCG3; FCGR3; IGFR3) (APC); anti-FCGR3B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human FCGR3B. Species Crossreactivity: human
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-FCGR3B antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Applications are based on unconjugated antibody.
Applications are based on unconjugated antibody.
Immunogen
KLH conjugated synthetic peptide corresponding to aa12-47 at the N-terminal region of human FCGR3B.
Conjugate
APC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Product Categories/Family for anti-FCGR3B antibody
References
Ravetch J.V., et al. J. Exp. Med. 170:481-497(1989). Simmons D., et al. Nature 333:568-570(1988). Simmons D., et al. Nature 340:662-662(1989). Peltz G.A., et al. Proc. Natl. Acad. Sci. U.S.A. 86:1013-1017(1989). Scallon B.J., et al. Proc. Natl. Acad. Sci. U.S.A. 86:5079-5083(1989).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
26,216 Da
NCBI Official Full Name
Low affinity immunoglobulin gamma Fc region receptor III-B
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIIb
NCBI Official Symbol
FCGR3B
NCBI Official Synonym Symbols
CD16; FCG3; CD16A; CD16b; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor III-B
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-B
Protein Family
UniProt Gene Name
FCGR3B
UniProt Synonym Gene Names
CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb
NCBI Description
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
Uniprot Description
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Research Articles on FCGR3B
Similar Products
Product Notes
The FCGR3B fcgr3b (Catalog #AAA6456097) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FCGR3B (Low affinity immunoglobulin gamma Fc Region Receptor III-B, Fc-gamma RIII-beta, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, FcR-10, IgG Fc Receptor III-1, CD16b, FCGR3B, CD16B, FCG3, FCGR3, IGFR3) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FCGR3B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the FCGR3B fcgr3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCGR3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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