Rabbit anti-Human BATF3 Polyclonal Antibody | anti-BATF3 antibody

BATF3 (Basic Leucine Zipper Transcriptional Factor ATF-like 3, B-ATF-3, 21kD Small Nuclear Factor isolated from T-Cells, Jun Dimerization Protein p21SNFT, BATF3, SNFT) (APC)

Cat. Num. AAA6454392

• Gene Names: BATF3; JDP1; SNFT; JUNDM1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: BATF3; Polyclonal Antibody; BATF3 (Basic Leucine Zipper Transcriptional Factor ATF-like 3; B-ATF-3; 21kD Small Nuclear Factor isolated from T-Cells; Jun Dimerization Protein p21SNFT; SNFT) (APC); anti-BATF3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human BATF3. Species Crossreactivity: human
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-BATF3 antibody: Western Blot (WB)
• Application Notes: WB: 1:2000; Applications are based on unconjugated antibody.
• Immunogen: KLH conjugated synthetic peptide corresponding to aa58-89 at the Central region of human BATF3.
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Categories/Family for anti-BATF3 antibody

Antibodies; Transcription Factors

References

Iacobelli M., et al. J. Immunol. 165:860-868(2000). Gregory S.G., et al. Nature 441:315-321(2006). Mural R.J., et al. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Bower K.E., et al. J. Biol. Chem. 277:34967-34977(2002). Bower K.E., et al. Oncogene 23:8805-8814(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 8924246
• NCBI GeneID: 55509
• NCBI Accession #: NP_061134
• NCBI GenBank Nucleotide #: NM_018664.2
• UniProt Accession #: Q9NR55
• Molecular Weight: Predicted: 14 kDa; ; Observed: 17 kDa
• NCBI Official Full Name: basic leucine zipper transcriptional factor ATF-like 3
• NCBI Official Synonym Full Names: basic leucine zipper transcription factor, ATF-like 3
• NCBI Official Symbol: BATF3
• NCBI Official Synonym Symbols: JDP1; SNFT; JUNDM1
• NCBI Protein Information: basic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; Jun dimerization protein 1; Jun dimerization protein p21SNFT; 21-kD small nuclear factor isolated from T cells; 21 kDa small nuclear factor isolated from T-cells
• UniProt Protein Name: Basic leucine zipper transcriptional factor ATF-like 3
• Protein Family: Basic leucine zipper transcriptional factor
• UniProt Gene Name: BATF3
• UniProt Synonym Gene Names: SNFT; B-ATF-3

NCBI Description

This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]

Uniprot Description

AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.