Goat FOXB1 Polyclonal Antibody | anti-foxb1 antibody

FOXB1 (Forkhead Box Protein B1, Transcription Factor FKH-5, FKH5)

Cat. Num. AAA643706

• Gene Names: foxb1; fkh5; fkh-5; xfkh-5
• Reactivity: Bovine, Canine, Human, Mouse, Porcine, Rat
• Applications: ELISA
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: FOXB1; Polyclonal Antibody; FOXB1 (Forkhead Box Protein B1; Transcription Factor FKH-5; FKH5); Anti -FOXB1 (Forkhead Box Protein B1; anti-foxb1 antibody

• Host: Goat
• Reactivity: Bovine, Canine, Human, Mouse, Porcine, Rat
• Clonality: Polyclonal
• Specificity: Recognizes mouse FOXB1. Species sequence homology: Bovine, canine, human, porcine and rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

• Applicable Applications for anti-foxb1 antibody: ELISA (EL/EIA)
• Application Notes: Suitable for use in ELISA.; Dilution: ELISA: 1:32,000
• Immunogen: Synthetic peptide corresponding to C-TSPASALHSVAVH, from mouse FOXB1, at C-terminal (NP_036314.2).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Categories/Family for anti-foxb1 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 148236087
• NCBI GeneID: 398078
• NCBI Accession #: NP_001081836.1
• NCBI GenBank Nucleotide #: NM_001088367.1
• UniProt Accession #: O93529
• Molecular Weight: 34,954 Da
• NCBI Official Full Name: forkhead box protein B1
• NCBI Official Synonym Full Names: forkhead box B1
• NCBI Official Symbol: foxb1
• NCBI Official Synonym Symbols: fkh5; fkh-5; xfkh-5
• NCBI Protein Information: forkhead box protein B1; transcription factor FKH-5; forkhead-domain-containing protein 5
• UniProt Protein Name: Forkhead box protein B1
• Protein Family: Forkhead box protein
• UniProt Gene Name: foxb1
• UniProt Synonym Gene Names: fkh5; FoxB1
• UniProt Entry Name: FOXB1_XENLA

Uniprot Description

Function: Probable transcription factor. May be involved in the early anteroposterior patterning of the neuroectoderm. Ref.1

Subcellular location: Nucleus

Probable.

Tissue specificity: In early gastrulae, expressed in the inner layer of the posterior dorsal ectoderm and in non-involuted mesoderm. By the mid-gastrula stage, expressed solely in the posterior ectoderm. At the end of gastrulation, expressed in ectodermal regions fated to become diencephalon, midbrain and hindbrain, and weakly expressed in regions fated to become spinal cord and tailbud. At the neurula stage, expressed in the midbrain and posterior forebrain (diencephalon) but not in the more anterior forebrain (telencephalon). Also expressed posteriorly in rhombomere 5. At tailbud stages, expression remains in the anterior brain and is also detectable along the length of the central nervous system and in the tailbud. Ref.1

Developmental stage: Expression begins in early gastrula stage embryos, peaks at the mid-gastrula stage and remains detectable until late tailbud. Ref.1

Induction: By FGF signaling. Ref.1

Sequence similarities: Contains 1 fork-head DNA-binding domain.