Rabbit CCNB2 Polyclonal Antibody | anti-CCNB2 antibody
CCNB2 (Cyclin B2, HsT17299) (HRP)
Applications are based on unconjugated antibody.
NCBI and Uniprot Product Information
NCBI Description
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]
Uniprot Description
CCNB2: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Belongs to the cyclin family. Cyclin AB subfamily.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: microtubule cytoskeleton; nucleoplasm; centrosome; membrane; cytosol
Molecular Function: protein binding; protein kinase binding
Biological Process: mitosis; thymus development; cell division; regulation of cell cycle; in utero embryonic development; mitotic nuclear envelope disassembly; T cell homeostasis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; growth