Western Blot (WB)
(Western Blot analysis of GPR50 expression in transfected 293T cell line by GPR50 polyclonal antibody. Lane 1: GPR50 transfected lysate (67.4kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human Melatonin-Related Receptor Polyclonal Antibody | anti-MTNRL antibody
Melatonin-Related Receptor (MTNRL, G-Protein-coupled Receptor 50, GPR50, H9, Mel1c, MGC125342) (AP)
Gene Names
GPR50; H9; Mel1c
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Melatonin-Related Receptor; Polyclonal Antibody; Melatonin-Related Receptor (MTNRL; G-Protein-coupled Receptor 50; GPR50; H9; Mel1c; MGC125342) (AP); anti-MTNRL antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human GPR50.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-MTNRL antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human GPR50, aa1-617 (AAI03697.1)
Immunogen Sequence
MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEETPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKPVSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGHHVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDYHDVVVVDVEDDPDEMAV
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of GPR50 expression in transfected 293T cell line by GPR50 polyclonal antibody. Lane 1: GPR50 transfected lysate (67.4kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of GPR50 expression in transfected 293T cell line by GPR50 polyclonal antibody. Lane 1: GPR50 transfected lysate (67.4kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-MTNRL antibody
Melatonin-related receptor is an Orphan-A GPCR with an unknown ligand. The receptor is related to high-affinity melatonin receptors, yet it is unable to bind the melatonin hormone. Melatonin-related receptor expression has been documented from human CNS tissues, specifically in hypothalamus and pituitary, but not in human peripheral tissues. In animals, expression has also been seen in the CNS, and peripheral tissues including adrenal, heart, kidney, lung, skin, intestine, stomach and testis.
Product Categories/Family for anti-MTNRL antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
67,369 Da
NCBI Official Full Name
Homo sapiens G protein-coupled receptor 50, mRNA
NCBI Official Synonym Full Names
G protein-coupled receptor 50
NCBI Official Symbol
GPR50
NCBI Official Synonym Symbols
H9; Mel1c
NCBI Protein Information
melatonin-related receptor
Protein Family
NCBI Description
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
Research Articles on MTNRL
Similar Products
Product Notes
The MTNRL (Catalog #AAA6385280) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Melatonin-Related Receptor (MTNRL, G-Protein-coupled Receptor 50, GPR50, H9, Mel1c, MGC125342) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Melatonin-Related Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MTNRL for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Melatonin-Related Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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