Paraoxonase 1 Recombinant Protein
Paraoxonase 1, Recombinant, Human (Paraoxonase-1, PON1, Aromatic Esterase 1, A-esterase 1, Esterase-A, ESA, K-45, Paraoxonase, PON, Serum Aryldialkylphosphatase 1, Serum Paraoxonase/arylesterase 1)
Purity
Highly Purified~95% (SDS-PAGE). Single band on Western Blot.
Synonyms
Paraoxonase 1; Recombinant; Human (Paraoxonase-1; PON1; Aromatic Esterase 1; A-esterase 1; Esterase-A; ESA; K-45; Paraoxonase; PON; Serum Aryldialkylphosphatase 1; Serum Paraoxonase/arylesterase 1); Paraoxonase 1 recombinant protein
Host
E Coli
Purity/Purification
Highly Purified
~95% (SDS-PAGE). Single band on Western Blot.
~95% (SDS-PAGE). Single band on Western Blot.
Form/Format
Supplied as a liquid in PBS, 50% glycerol.
Sequence
MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLRSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCELZ
Application Notes
Suitable to be used directly as a positive control in Western Blot, ELISA, Immunoprecipitation and other immunological experiments.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Paraoxonase 1 recombinant protein
Paraoxonase 1 also called Esterase-A is involved in the detoxification of organophosphate insecticides such as parathion. Paraoxonase 1 may also confer protection against coronary artery disease by destroying proinflammatory oxidized lipids present in oxidized low-density lipoproteins (LDLs).
Recombinant Human Paraoxonase-1 is expressed in E. coli having a molecular weight of 42.9kD and fused to an amino terminal hexahistidine tag. The biological activity of this product has not yet been tested.
Recombinant Human Paraoxonase-1 is expressed in E. coli having a molecular weight of 42.9kD and fused to an amino terminal hexahistidine tag. The biological activity of this product has not yet been tested.
Product Categories/Family for Paraoxonase 1 recombinant protein
NCBI and Uniprot Product Information
NCBI Description
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq, Oct 2008]
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Product Notes
The Paraoxonase 1 (Catalog #AAA638080) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Suitable to be used directly as a positive control in Western Blot, ELISA, Immunoprecipitation and other immunological experiments. Researchers should empirically determine the suitability of the Paraoxonase 1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAKLIALTLL GMGLALFRNH QSSYQTRLNA LREVQPVELP NCNLVKGIET GSEDLEILPN GLAFISSGLK YPGIKSFNPN SPGKILLMDL NEEDPTVLEL GITGSKFDVS SFNPHGISTF TDEDNAMYLL VVNHPDAKST VELFKFQEEE KSLLHLKTIR HKLLPNLNDI VAVGPEHFYG TNDHYFLDPY LRSWEMYLGL AWSYVVYYSP SEVRVVAEGF DFANGINISP DGKYVYIAEL LAHKIHVYEK HANWTLTPLK SLDFNTLVDN ISVDPETGDL WVGCHPNGMK IFFYDSENPP ASEVLRIQNI LTEEPKVTQV YAENGTVLQG STVASVYKGK LLIGTVFHKA LYCELZ. It is sometimes possible for the material contained within the vial of "Paraoxonase 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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