SDS-Page
(Figure 1. 10% SDS-PAGE Coomassie staining of G1019-60A. Lane 1: 7ug Galactokinase, Lane 2: Molecular weight markers.)
Galactokinase Active Protein | GALK1 active protein
Galactokinase, Recombinant, Human (Galactokinase 1, GALK1, Galactose Kinase)
~90%
~90%
SDS-Page
(Figure 1. 10% SDS-PAGE Coomassie staining of G1019-60A. Lane 1: 7ug Galactokinase, Lane 2: Molecular weight markers.)
SDS-Page
(Figure 1. 10% SDS-PAGE Coomassie staining of G1019-60A. Lane 1: 7ug Galactokinase, Lane 2: Molecular weight markers.)
Testing Data
(244 pmoles/min/ug. A 50ul Galactokinase reaction is conducted|in a buffer containing 20 mM Tris (pH 7.4),5 mM MgCl2, 50 mM NaCl, 5 μM ATP, 1mM DTT and 1 mM substrate D-Galactose at RT for 1h. ATP reduction isdetected using Kinase-Glo Luminescent Kinase Assay Platform.)
Testing Data
(244 pmoles/min/ug. A 50ul Galactokinase reaction is conducted|in a buffer containing 20 mM Tris (pH 7.4),5 mM MgCl2, 50 mM NaCl, 5 μM ATP, 1mM DTT and 1 mM substrate D-Galactose at RT for 1h. ATP reduction isdetected using Kinase-Glo Luminescent Kinase Assay Platform.)
NCBI and Uniprot Product Information
NCBI Description
Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008]
Uniprot Description
GALK1: Major enzyme for galactose metabolism. Defects in GALK1 are the cause of galactosemia II (GALCT2). Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses. Belongs to the GHMP kinase family. GalK subfamily.
Protein type: Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Kinase, other; EC 2.7.1.6
Chromosomal Location of Human Ortholog: 17q24
Cellular Component: membrane; cytoplasm; cytosol
Molecular Function: galactokinase activity; galactose binding; ATP binding
Biological Process: galactose catabolic process; carbohydrate metabolic process; carbohydrate phosphorylation; galactitol metabolic process; galactose metabolic process; pathogenesis
Disease: Galactokinase Deficiency
Research Articles on GALK1
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Product Notes
The GALK1 galk1 (Catalog #AAA638026) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Researchers should empirically determine the suitability of the GALK1 galk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Galactokinase, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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