Western Blot (WB)
(Western Blot analysis of FMO2 expression in transfected 293T cell line by FMO2 polyclonal antibody. Lane 1: FMO2 transfected lysate (53.6kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human FMO2 Polyclonal Antibody | anti-FMO2 antibody
FMO2 (Dimethylaniline Monooxygenase [N-oxide-forming] 2, Pulmonary Flavin-containing Monooxygenase 2, FMO 2, FMO 1B1, Dimethylaniline Oxidase 2) (Biotin)
Gene Names
FMO2; FMO1B1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
FMO2; Polyclonal Antibody; FMO2 (Dimethylaniline Monooxygenase [N-oxide-forming] 2; Pulmonary Flavin-containing Monooxygenase 2; FMO 2; FMO 1B1; Dimethylaniline Oxidase 2) (Biotin); anti-FMO2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human FMO2.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-FMO2 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human FMO2, aa1-471 (NP_001451.1).
Immunogen Sequence
MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAHLDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRIDLFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSY
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of FMO2 expression in transfected 293T cell line by FMO2 polyclonal antibody. Lane 1: FMO2 transfected lysate (53.6kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of FMO2 expression in transfected 293T cell line by FMO2 polyclonal antibody. Lane 1: FMO2 transfected lysate (53.6kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-FMO2 antibody
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein represents the truncated form and apparently has no catalytic activity.
Product Categories/Family for anti-FMO2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,644 Da
NCBI Official Full Name
dimethylaniline monooxygenase
NCBI Official Synonym Full Names
flavin containing monooxygenase 2 (non-functional)
NCBI Official Symbol
FMO2
NCBI Official Synonym Symbols
FMO1B1
NCBI Protein Information
dimethylaniline monooxygenase [N-oxide-forming] 2; dimethylaniline monooxygenase [N-oxide-forming] 2; FMO, pulmonary; dimethylaniline oxidase 2; pulmonary flavin-containing monooxygenase 2
UniProt Protein Name
Dimethylaniline monooxygenase [N-oxide-forming] 2
Protein Family
UniProt Gene Name
FMO2
UniProt Synonym Gene Names
FMO 2
UniProt Entry Name
FMO2_HUMAN
Uniprot Description
FMO2: Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive. Belongs to the FMO family.
Protein type: EC 1.14.13.8; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase
Chromosomal Location of Human Ortholog: 1q24.3
Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane
Molecular Function: FAD binding; NADP binding; monooxygenase activity; flavin-containing monooxygenase activity
Biological Process: organic acid metabolic process; toxin metabolic process; xenobiotic metabolic process; drug metabolic process; NADP metabolic process
Similar Products
Product Notes
The FMO2 fmo2 (Catalog #AAA6378737) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FMO2 (Dimethylaniline Monooxygenase [N-oxide-forming] 2, Pulmonary Flavin-containing Monooxygenase 2, FMO 2, FMO 1B1, Dimethylaniline Oxidase 2) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FMO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the FMO2 fmo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FMO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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