Western Blot (WB)
(Western Blot analysis of CREBL2 expression in transfected 293T cell line by CREBL2 polyclonal antibody. Lane 1: CREBL2 transfected lysate (13.8kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human CREBL2 Polyclonal Antibody | anti-CREBL2 antibody
CREBL2 (cAMP-responsive Element-binding Protein-like 2) APC
Gene Names
CREBL2; MGC117311; MGC138362
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
CREBL2; Polyclonal Antibody; CREBL2 (cAMP-responsive Element-binding Protein-like 2) APC; anti-CREBL2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CREBL2.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-CREBL2 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human CREBL2, aa1-120 (NP_001301.1)
Immunogen Sequence
MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIKALLTGEEQNKSQQNSSRHTKAGKTDANSNSW
Conjugate
APC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of CREBL2 expression in transfected 293T cell line by CREBL2 polyclonal antibody. Lane 1: CREBL2 transfected lysate (13.8kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CREBL2 expression in transfected 293T cell line by CREBL2 polyclonal antibody. Lane 1: CREBL2 transfected lysate (13.8kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-CREBL2 antibody
cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene.
Product Categories/Family for anti-CREBL2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,784 Da
NCBI Official Full Name
cAMP-responsive element-binding protein-like 2
NCBI Official Synonym Full Names
cAMP responsive element binding protein-like 2
NCBI Official Symbol
CREBL2
NCBI Official Synonym Symbols
MGC117311; MGC138362
NCBI Protein Information
cAMP-responsive element-binding protein-like 2; OTTHUMP00000239221
UniProt Protein Name
cAMP-responsive element-binding protein-like 2
Protein Family
UniProt Gene Name
CREBL2
UniProt Entry Name
CRBL2_HUMAN
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Product Notes
The CREBL2 crebl2 (Catalog #AAA6374699) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CREBL2 (cAMP-responsive Element-binding Protein-like 2) APC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CREBL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CREBL2 crebl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CREBL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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