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Western Blot (WB) (ZFP36L2 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ZFP36L2 antibody detected the ZFP36L2 protein (arrow).)

Rabbit anti-Human, Mouse ZFP36L2 Polyclonal Antibody | anti-ZFP36L2 antibody

ZFP36L2, ID (ZFP36L2, BRF2, ERF2, RNF162C, TIS11D, Zinc finger protein 36, C3H1 type-like 2, Butyrate response factor 2, EGF-response factor 2, Protein TIS11D) (Biotin)

Gene Names
ZFP36L2; BRF2; ERF2; ERF-2; TIS11D; RNF162C
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ZFP36L2; Polyclonal Antibody; ID (ZFP36L2; BRF2; ERF2; RNF162C; TIS11D; Zinc finger protein 36; C3H1 type-like 2; Butyrate response factor 2; EGF-response factor 2; Protein TIS11D) (Biotin); Protein TIS11D; anti-ZFP36L2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-ZFP36L2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
ZFP36L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-193 amino acids from the Central region of human ZFP36L2.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ZFP36L2 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ZFP36L2 antibody detected the ZFP36L2 protein (arrow).)

Western Blot (WB) (ZFP36L2 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ZFP36L2 antibody detected the ZFP36L2 protein (arrow).)

Western Blot (WB)

(ZFP36L2 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ZFP36L2 antibody detected the ZFP36L2 protein (arrow).)

Western Blot (WB) (ZFP36L2 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the ZFP36L2 antibody detected the ZFP36L2 protein (arrow).)
Related Product Information for anti-ZFP36L2 antibody
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
Product Categories/Family for anti-ZFP36L2 antibody
References
Morgan, B.R., et al. Protein Sci. 19(6):1222-1234(2010). Jackson, R.S. II, et al. Cell Cycle 5(24):2889-2893(2006). Hudson, B.P., et al. Nat. Struct. Mol. Biol. 11(3):257-264(2004). Blackshear, P.J., et al. Prog. Nucleic Acid Res. Mol. Biol. 75, 43-68 (2003): Ino, T., et al. Oncogene 11(12):2705-2710(1995).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
678
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,063 Da
NCBI Official Full Name
zinc finger protein 36, C3H1 type-like 2
NCBI Official Synonym Full Names
ZFP36 ring finger protein-like 2
NCBI Official Symbol
ZFP36L2
NCBI Official Synonym Symbols
BRF2; ERF2; ERF-2; TIS11D; RNF162C
NCBI Protein Information
zinc finger protein 36, C3H1 type-like 2; ZFP36-like 2; EGF-response factor 2; butyrate response factor 2; zinc finger protein 36, C3H type-like 1; zinc finger protein 36, C3H type-like 2; zinc finger protein, C3H type, 36-like 2
UniProt Protein Name
Zinc finger protein 36, C3H1 type-like 2
UniProt Gene Name
ZFP36L2
UniProt Synonym Gene Names
BRF2; ERF2; RNF162C; TIS11D; ZFP36-like 2; ERF-2
UniProt Entry Name
TISD_HUMAN

NCBI Description

This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. [provided by RefSeq, Jul 2008]

Uniprot Description

ZFP36L2: Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 2p22.3-p21

Cellular Component: cytoplasm; nucleus

Molecular Function: DNA binding; metal ion binding; AU-rich element binding; transcription factor activity

Biological Process: cell proliferation; regulation of transcription, DNA-dependent; somatic stem cell maintenance; mRNA catabolic process; T cell differentiation in the thymus; somatic stem cell division; hemopoiesis; regulation of mRNA stability; mRNA catabolic process, deadenylation-dependent decay

Research Articles on ZFP36L2

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Product Notes

The ZFP36L2 zfp36l2 (Catalog #AAA6365152) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZFP36L2, ID (ZFP36L2, BRF2, ERF2, RNF162C, TIS11D, Zinc finger protein 36, C3H1 type-like 2, Butyrate response factor 2, EGF-response factor 2, Protein TIS11D) (Biotin) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZFP36L2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ZFP36L2 zfp36l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZFP36L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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