Rabbit anti-Human, Mouse TOR1B Polyclonal Antibody | anti-TOR1B antibody

TOR1B, ID (TOR1B, DQ1, Torsin-1B, Torsin family 1 member B) (APC)

Cat. Num. AAA6357429

• Gene Names: TOR1B; DQ1
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TOR1B; Polyclonal Antibody; ID (TOR1B; DQ1; Torsin-1B; Torsin family 1 member B) (APC); Torsin family 1 member B; anti-TOR1B antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-TOR1B antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TOR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216~246 amino acids from the Central region of human TOR1B.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(TOR1B Antibody (Center) western blot analysis in 293,MCF-7,MDA-MB231,MDA-MB435,and mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the TOR1B antibody detected the TOR1B protein (arrow).)

Related Product Information for anti-TOR1B antibody

TOR1B may serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins.

Product Categories/Family for anti-TOR1B antibody

Antibodies; Proteins

References

Kamm, C., et al. Neurology 67(10):1857-1859(2006). Bahn, E., et al. Brain Res. 1116(1):112-119(2006). Hewett, J.W., et al. J. Neurochem. 89(5):1186-1194(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 14149653
• NCBI GeneID: 27348
• NCBI Accession #: NP_055321.1
• NCBI GenBank Nucleotide #: NM_014506.2
• UniProt Accession #: O14657
• Molecular Weight: 37,979 Da
• NCBI Official Full Name: torsin-1B isoform 1
• NCBI Official Synonym Full Names: torsin family 1 member B
• NCBI Official Symbol: TOR1B
• NCBI Official Synonym Symbols: DQ1
• NCBI Protein Information: torsin-1B
• UniProt Protein Name: Torsin-1B
• Protein Family: Torsin
• UniProt Gene Name: TOR1B
• UniProt Synonym Gene Names: DQ1

NCBI Description

The protein encoded by this gene is an ATPase found primarily in the endoplasmic reticulum and nuclear envelope. This gene has a highly-similar neighboring gene, TOR1A, that encodes a protein that is likely to interact in a complex with this protein. Finally, this protein may act as a chaperone and play a role in maintaining the integrity of the nuclear envelope and endoplasmic reticulum. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]

Uniprot Description

May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity. May have a redundant function with TOR1A in non-neural tissues.