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Western Blot (WB) (Western blot analysis of TOMM70A Antibody (N-term) in WiDr cell line lysates (35ug/lane). TOMM70A (arrow) was detected using the purified Pab.)

Rabbit anti-Human TOMM70A Polyclonal Antibody | anti-TOMM70A antibody

TOMM70A, NT (TOMM70A, KIAA0719, TOM70, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70kD subunit) (PE)

Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
TOMM70A; Polyclonal Antibody; NT (TOMM70A; KIAA0719; TOM70; Mitochondrial import receptor subunit TOM70; Mitochondrial precursor proteins import receptor; Translocase of outer membrane 70kD subunit) (PE); mitochondrial import receptor subunit TOM70; mitochondrial precursor proteins import receptor; Translocase of outer membrane 70kD subunit; anti-TOMM70A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-TOMM70A antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
TOMM70A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184~214 amino acids from the N-terminal region of human TOMM70A.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of TOMM70A Antibody (N-term) in WiDr cell line lysates (35ug/lane). TOMM70A (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of TOMM70A Antibody (N-term) in WiDr cell line lysates (35ug/lane). TOMM70A (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human brain tissue reacted with TOMM70A Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human brain tissue reacted with TOMM70A Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Related Product Information for anti-TOMM70A antibody
The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria.
Product Categories/Family for anti-TOMM70A antibody
References
Blesa, J.R., et.al., Gene 427 (1-2), 58-64 (2008). Chou, C.H., et.al., Mol. Biol. Cell 17 (9), 3952-3963 (2006). Edmonson, A.M., et.al., Cell Commun. Adhes. 9 (1), 15-27 (2002).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
608
NCBI Official Full Name
Mitochondrial import receptor subunit TOM70
NCBI Official Synonym Full Names
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
NCBI Official Symbol
TOMM70A
NCBI Protein Information
mitochondrial import receptor subunit TOM70; translocase of outer membrane 70 kDa subunit; mitochondrial precursor proteins import receptor
UniProt Protein Name
Mitochondrial import receptor subunit TOM70
UniProt Gene Name
TOMM70A
UniProt Synonym Gene Names
KIAA0719; TOM70
UniProt Entry Name
TOM70_HUMAN

NCBI Description

This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. [provided by RefSeq, Oct 2011]

Uniprot Description

TOMM70A: Receptor that accelerates the import of all mitochondrial precursor proteins. Belongs to the Tom70 family.

Protein type: Receptor, protein translocating; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q12.2

Cellular Component: membrane; mitochondrial outer membrane translocase complex; mitochondrion; integral to membrane

Molecular Function: protein binding; protein transmembrane transporter activity

Biological Process: cellular protein metabolic process; protein targeting to mitochondrion

Research Articles on TOMM70A

Similar Products

Product Notes

The TOMM70A tomm70a (Catalog #AAA6357350) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TOMM70A, NT (TOMM70A, KIAA0719, TOM70, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70kD subunit) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TOMM70A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:50-100 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TOMM70A tomm70a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TOMM70A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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