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WNT9B active protein

Wnt9b, Recombinant, Mouse (Wnt-14b, Wnt-15, Wingless-type MMTV (Mouse Mammary Tumor Virus) Integration Site Family Member)

Gene Names
WNT9B; WNT15; WNT14B
Purity
Purified
Purified
Synonyms
Wnt9b; Recombinant; Mouse (Wnt-14b; Wnt-15; Wingless-type MMTV (Mouse Mammary Tumor Virus) Integration Site Family Member); WNT9B active protein
Ordering
For Research Use Only!
Purity/Purification
Purified
Purified
Form/Format
Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 0.1mm EDTA, 0.5% CHAPS, pH 6.8, 50ug BSA/1ug of cytokine. Reconstitute with 40-50% glycerol, PBS.
Activity
Measured by its ability to induce alkaline phosphatase synthesis by C3H10T1/2 cells (ATCC,
The typical ED 50 range is 100-400ng/ml.

Storage and Stability:
12 months from date of receipt, 20 to 70 degree C as supplied.
1 month, 2 to 8 degree C under sterile conditions after reconstitution.
3 months, 20 to 70 degree C under sterile conditions after reconstitution.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Preparation and Storage
4 degree C Do Not Freeze
Related Product Information for WNT9B active protein
Mouse Wnt-9b, previously called Wnt-14b or Wnt-15, is one of at least 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved, cysteine-rich secreted glycoproteins that are important for normal developmental processes (1-3). Wnts
Product Categories/Family for WNT9B active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Based on N-terminal aa sequencing, the recombinant mouse Wnt-9b starts at Ala 24 and has a calculated molecular mass of approximately 36.8kD. The recombinant mouse Wnt-9b migrates as an approximately 39-41kD protein in SDS-PAGE under reducing conditions.
NCBI Official Full Name
WNT9B
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 9B
NCBI Official Symbol
WNT9B
NCBI Official Synonym Symbols
WNT15; WNT14B
NCBI Protein Information
protein Wnt-9b; protein Wnt-14b; wingless-type MMTV integration site family, member 15
UniProt Protein Name
Protein Wnt-9b
Protein Family
UniProt Gene Name
WNT9B
UniProt Synonym Gene Names
WNT14B; WNT15
UniProt Entry Name
WNT9B_HUMAN

NCBI Description

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]

Uniprot Description

WNT9B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: frizzled binding

Biological Process: positive regulation of catalytic activity; regulation of protein amino acid phosphorylation; Wnt receptor signaling pathway; cell fate commitment; response to retinoic acid; regulation of asymmetric cell division; Wnt receptor signaling pathway, planar cell polarity pathway; in utero embryonic development; multicellular organismal development; Wnt receptor signaling pathway through beta-catenin; palate development; embryonic cranial skeleton morphogenesis; cellular response to starvation; neuron differentiation; cell-cell signaling; ureteric bud branching; male genitalia development; regulation of tube size

Research Articles on WNT9B

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Product Notes

The WNT9B wnt9b (Catalog #AAA635545) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Wnt9b, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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