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Casein Kinase 1 Substrate Protein | CK1 protein

Casein Kinase 1 Substrate

Gene Names
CK1; casein kinase 1; CK1; CKL1
Purity
Highly Purified
~95%
Synonyms
Casein Kinase 1 Substrate; CK1 protein
Ordering
For Research Use Only!
Host
Synthetic peptide
Purity/Purification
Highly Purified
~95%
Form/Format
Supplied as a liquid; 1mg packaged in two vials, each vial containing 500ug peptide in 100ul sterile, distilled water (2.3mM).
Application Notes
Suitable for use in Kinase assay.
Dilution: Protein Kinase Assay: 250uM of this lot of substrate peptide was phosphorylated by a 1:100 dilution of Casein Kinase 1d (aa 1-294), active.
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for CK1 protein
Synthetic peptide based around an Inhibitor-2 peptide sequence that is phosphorylated by Casein Kinase 1 (RRKDLHDDEEDEAMSITA) (linear). Two amino acid substitutions have been made to render the peptide refractory to Casein Kinase 2. The substitutions, which are underscored, are both glutamate residues in Inhibitor 2.
Product Categories/Family for CK1 protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,947 Da
NCBI Official Full Name
casein kinase 1
NCBI Official Symbol
CK1
NCBI Official Synonym Symbols
casein kinase 1; CK1; CKL1
NCBI Protein Information
casein kinase 1
UniProt Protein Name
Casein kinase I isoform delta-like
Protein Family
UniProt Gene Name
CKI-delta
UniProt Synonym Gene Names
CKI-delta
UniProt Entry Name
KC1D_ARATH

NCBI Description

Encodes a member of the casein kinase 1 protein family that is expressed in punctate particles at the cell periphery suggesting possible plasmodesmatal localization.

Uniprot Description

Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins.

Catalytic activity: ATP + a protein = ADP + a phosphoprotein.

Subunit structure: Monomer

By similarity.

Subcellular location: Cytoplasm

By similarity.

Post-translational modification: Autophosphorylated

By similarity.

Sequence similarities: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.Contains 1 protein kinase domain.

Sequence caution: The sequence AAA50233.1 differs from that shown. Reason: Frameshift at positions 381 and 414.

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Product Notes

The CK1 cki-delta (Catalog #AAA635174) is a Protein produced from Synthetic peptide and is intended for research purposes only. The product is available for immediate purchase. Suitable for use in Kinase assay. Dilution: Protein Kinase Assay: 250uM of this lot of substrate peptide was phosphorylated by a 1:100 dilution of Casein Kinase 1d (aa 1-294), active. Researchers should empirically determine the suitability of the CK1 cki-delta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Casein Kinase 1 Substrate, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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