Mouse anti-Human CD41a Monoclonal Antibody
CD41a
Reactivity
Human
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
CD41a; Monoclonal Antibody; Anti -CD41a; anti-CD41a antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
HIP8
Specificity
Recognizes human CD41 molecule.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH7.4, 15mM sodium azide.
Applicable Applications for anti-CD41a antibody
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry and Immunohistochemistry.
Dilution: Flow Cytometry: 0.5mg labels 1x10e6 of human platelets in 100ml of blood.
Immunohistochemistry: Frozen
Dilution: Flow Cytometry: 0.5mg labels 1x10e6 of human platelets in 100ml of blood.
Immunohistochemistry: Frozen
Immunogen
Human CD41a
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-CD41a antibody
The CD41 molecule is the integrin alphaIIb also known as platelet GPIIb. CD41 non-covalently associates with betaIII integrin (GPIIIa, CD61) and is expressed by megakaryocytes and platelets. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin and mediates platelets aggregation. This antibody blocks platelet aggregation. CD41 completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes. The GPIIb/IIIa may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).
Product Categories/Family for anti-CD41a antibody
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Product Notes
The CD41a (Catalog #AAA632820) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD41a reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD41a can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry and Immunohistochemistry. Dilution: Flow Cytometry: 0.5mg labels 1x10e6 of human platelets in 100ml of blood. Immunohistochemistry: Frozen. Researchers should empirically determine the suitability of the CD41a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD41a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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