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Western Blot (WB) (ODC1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ODC1 antibody detected the ODC1 protein (arrow).)

Rabbit anti-Human ODC1 Polyclonal Antibody | anti-ODC1 antibody

ODC1, CT (ODC1, Ornithine decarboxylase) (AP)

Gene Names
ODC1; ODC
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ODC1; Polyclonal Antibody; CT (ODC1; Ornithine decarboxylase) (AP); Ornithine decarboxylase; anti-ODC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-ODC1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
ODC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ODC1.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ODC1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ODC1 antibody detected the ODC1 protein (arrow).)

Western Blot (WB) (ODC1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ODC1 antibody detected the ODC1 protein (arrow).)
Related Product Information for anti-ODC1 antibody
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
Product Categories/Family for anti-ODC1 antibody
References
Chaturvedi, R., et al. Gastroenterology 139(5):1686-1698(2010). Zell, J.A., et al. J. Natl. Cancer Inst. 102(19):1513-1516(2010). Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010). Hughes, D., et al. Colorectal Dis (2010). In press: Grimminger, P.P., et al. Clin Lung Cancer 11(2):114-119(2010).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,148 Da
NCBI Official Full Name
ornithine decarboxylase
NCBI Official Synonym Full Names
ornithine decarboxylase 1
NCBI Official Symbol
ODC1
NCBI Official Synonym Symbols
ODC
NCBI Protein Information
ornithine decarboxylase
UniProt Protein Name
Ornithine decarboxylase
UniProt Gene Name
ODC1
UniProt Synonym Gene Names
ODC
UniProt Entry Name
DCOR_HUMAN

NCBI Description

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]

Uniprot Description

ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]

Protein type: EC 4.1.1.17; Amino Acid Metabolism - arginine and proline; Other Amino Acids Metabolism - glutathione; Cell cycle regulation; Lyase

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: cytoplasm; cytosol

Molecular Function: protein homodimerization activity; ornithine decarboxylase activity

Biological Process: response to virus; positive regulation of cell proliferation; regulation of protein catabolic process; kidney development; regulation of amino acid metabolic process; putrescine biosynthetic process from ornithine; polyamine metabolic process

Disease: Colorectal Cancer

Research Articles on ODC1

Similar Products

Product Notes

The ODC1 odc1 (Catalog #AAA6327601) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ODC1, CT (ODC1, Ornithine decarboxylase) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ODC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ODC1 odc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ODC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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