Western Blot (WB)
(NFE2L3 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NFE2L3 antibody detected the NFE2L3 protein (arrow).)
Rabbit anti-Human NFE2L3 Polyclonal Antibody | anti-NFE2L3 antibody
NFE2L3, CT (NFE2L3, NRF3, Nuclear factor erythroid 2-related factor 3, Nuclear factor, erythroid derived 2, like 3) (PE)
Gene Names
NFE2L3; NRF3
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
NFE2L3; Polyclonal Antibody; CT (NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; Nuclear factor; erythroid derived 2; like 3) (PE); like 3; anti-NFE2L3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-NFE2L3 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
NFE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-694 amino acids from the C-terminal region of human NFE2L3.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(NFE2L3 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NFE2L3 antibody detected the NFE2L3 protein (arrow).)
Western Blot (WB)
(NFE2L3 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NFE2L3 antibody detected the NFE2L3 protein (arrow).)
Related Product Information for anti-NFE2L3 antibody
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
Product Categories/Family for anti-NFE2L3 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Davila, S., et al. Genes Immun. 11(3):232-238(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Zhang, Y., et al. J. Biol. Chem. 284(5):3195-3210(2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
76,154 Da
NCBI Official Full Name
nuclear factor erythroid 2-related factor 3
NCBI Official Synonym Full Names
nuclear factor (erythroid-derived 2)-like 3
NCBI Official Symbol
NFE2L3
NCBI Official Synonym Symbols
NRF3
NCBI Protein Information
nuclear factor erythroid 2-related factor 3; NFE2-related factor 3; NF-E2-related factor 3; nuclear factor, erythroid derived 2, like 3; nuclear factor-erythroid 2-related factor 3; nuclear factor-erythroid 2 p45-related factor 3
UniProt Protein Name
Nuclear factor erythroid 2-related factor 3
Protein Family
UniProt Gene Name
NFE2L3
UniProt Synonym Gene Names
NRF3; NF-E2-related factor 3
UniProt Entry Name
NF2L3_HUMAN
NCBI Description
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]
Uniprot Description
NFE2L3: Activates erythroid-specific, globin gene expression. Belongs to the bZIP family. CNC subfamily.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 7p15.2
Cellular Component: nucleus
Molecular Function: transcription coactivator activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter
Research Articles on NFE2L3
1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
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Product Notes
The NFE2L3 nfe2l3 (Catalog #AAA6324992) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NFE2L3, CT (NFE2L3, NRF3, Nuclear factor erythroid 2-related factor 3, Nuclear factor, erythroid derived 2, like 3) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NFE2L3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the NFE2L3 nfe2l3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NFE2L3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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