Rabbit anti-Human, Mouse MOL2B Polyclonal Antibody | anti-MOL2B antibody

MOL2B, NT (MOB3B, MOBKL2B, MOB kinase activator 3B, Mob1 homolog 2b, Mps one binder kinase activator-like 2B) (PE)

Cat. Num. AAA6321679

• Gene Names: MOB3B; MOB1D; C9orf35; MOBKL2B
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MOL2B; Polyclonal Antibody; NT (MOB3B; MOBKL2B; MOB kinase activator 3B; Mob1 homolog 2b; Mps one binder kinase activator-like 2B) (PE); MOB3B; Mps one binder kinase activator-like 2B; anti-MOL2B antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-MOL2B antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: MOL2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MOL2B.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(MOL2B Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOL2B antibody detected the MOL2B protein (arrow).)

Related Product Information for anti-MOL2B antibody

The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene.

Product Categories/Family for anti-MOL2B antibody

Antibodies; Protein Kinases

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Smith, N.L., et al. Circ Cardiovasc Genet 3(3):256-266(2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Suarez-Gestal, M., et al. Arthritis Res. Ther. 12 (2), R72 (2010): van Es, M.A., et al. Nat. Genet. 41(10):1083-1087(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 41350330
• NCBI GeneID: 79817
• NCBI Accession #: NP_079037.3
• NCBI GenBank Nucleotide #: NM_024761.4
• UniProt Accession #: Q86TA1; Q8NEB4; Q9H8V4
• Molecular Weight: 25,464 Da
• NCBI Official Full Name: MOB kinase activator 3B
• NCBI Official Synonym Full Names: MOB kinase activator 3B
• NCBI Official Symbol: MOB3B
• NCBI Official Synonym Symbols: MOB1D; C9orf35; MOBKL2B
• NCBI Protein Information: MOB kinase activator 3B; mob1 homolog 2b; mps one binder kinase activator-like 2B; MOB1, Mps One Binder kinase activator-like 2B; monopolar spindle 1 binding, MOB1, domain containing
• UniProt Protein Name: MOB kinase activator 3B
• UniProt Gene Name: MOB3B
• UniProt Synonym Gene Names: MOBKL2B
• UniProt Entry Name: MOB3B_HUMAN

NCBI Description

The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]

Uniprot Description

MOBKL2B: May regulate the activity of kinases. Belongs to the MOB1/phocein family.

Chromosomal Location of Human Ortholog: 9p21.2

Molecular Function: protein binding; metal ion binding