Rabbit anti-Human KCNG2 Polyclonal Antibody | anti-KCNG2 antibody

KCNG2, ID (KCNG2, KCNF2, Potassium voltage-gated channel subfamily G member 2, Cardiac potassium channel subunit, Voltage-gated potassium channel subunit Kv6.2) (FITC)

Cat. Num. AAA6312415

• Gene Names: KCNG2; KCNF2; KV6.2
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: KCNG2; Polyclonal Antibody; ID (KCNG2; KCNF2; Potassium voltage-gated channel subfamily G member 2; Cardiac potassium channel subunit; Voltage-gated potassium channel subunit Kv6.2) (FITC); Voltage-gated potassium channel subunit Kv6.2; anti-KCNG2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-KCNG2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KCNG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the Central region of human KCNG2.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(KCNG2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the KCNG2 antibody detected the KCNG2 protein (arrow).)

Related Product Information for anti-KCNG2 antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization. [provided by RefSeq].

Product Categories/Family for anti-KCNG2 antibody

Antibodies; Ion Channel

References

Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005). Zhu, X.R., et al. Recept. Channels 6(5):337-350(1999).

NCBI and Uniprot Product Information

• NCBI GI #: 6912444
• NCBI GeneID: 26251
• NCBI Accession #: NP_036415.1
• NCBI GenBank Nucleotide #: NM_012283.1
• UniProt Accession #: Q9UJ96
• Molecular Weight: 51,240 Da
• NCBI Official Full Name: potassium voltage-gated channel subfamily G member 2
• NCBI Official Synonym Full Names: potassium voltage-gated channel, subfamily G, member 2
• NCBI Official Symbol: KCNG2
• NCBI Official Synonym Symbols: KCNF2; KV6.2
• NCBI Protein Information: potassium voltage-gated channel subfamily G member 2; cardiac potassium channel subunit; voltage-gated potassium channel subunit Kv6.2
• UniProt Protein Name: Potassium voltage-gated channel subfamily G member 2
• Protein Family: Potassium voltage-gated channel subfamily
• UniProt Gene Name: KCNG2
• UniProt Synonym Gene Names: KCNF2
• UniProt Entry Name: KCNG2_HUMAN

NCBI Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization. [provided by RefSeq, Jul 2008]

Uniprot Description

Kv6.2: Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.2/KCNG2 sub-subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 18q23

Cellular Component: voltage-gated potassium channel complex; integral to membrane; plasma membrane

Molecular Function: delayed rectifier potassium channel activity

Biological Process: synaptic transmission; energy reserve metabolic process; regulation of insulin secretion; regulation of heart contraction; protein homooligomerization; potassium ion transport