Rabbit anti-Human GPATCH4 Polyclonal Antibody | anti-GPATCH4 antibody

GPATCH4, ID (GPATCH4, GPATC4, G patch domain-containing protein 4) (PE)

Cat. Num. AAA6303446

• Gene Names: GPATCH4; GPATC4
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GPATCH4; Polyclonal Antibody; ID (GPATCH4; GPATC4; G patch domain-containing protein 4) (PE); G patch domain-containing protein 4; anti-GPATCH4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-GPATCH4 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GPATCH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-262 amino acids from the Central region of human GPATCH4.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GPATCH4 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GPATCH4 antibody detected the GPATCH4 protein (arrow).)

Related Product Information for anti-GPATCH4 antibody

GPATCH4 (G patch domain-containing protein 4) is a 446 amino acid protein containing one G-patch domain. Existing as three alternatively spliced isoforms, the gene encoding GPATCH4 maps to human chromosome 1q23.1 and mouse chromosome 3 F1. Spanning around 260 million base pairs, chromosome 1 is the largest human chromosome and comprises 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Product Categories/Family for anti-GPATCH4 antibody

Antibodies; Disease Markers

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Olsen, J.V., et al. Cell 127(3):635-648(2006). Andersen, J.S., et al. Nature 433(7021):77-83(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 33356552
• NCBI GeneID: 54865
• NCBI Accession #: NP_056405.2
• NCBI GenBank Nucleotide #: NM_015590.3
• UniProt Accession #: Q5T3I0; Q5T3I1; Q6ZUE7; Q8IWG8; Q9NXH4
• Molecular Weight: 50,381 Da
• NCBI Official Full Name: G patch domain-containing protein 4 isoform 1
• NCBI Official Synonym Full Names: G patch domain containing 4
• NCBI Official Symbol: GPATCH4
• NCBI Official Synonym Symbols: GPATC4
• NCBI Protein Information: G patch domain-containing protein 4
• UniProt Protein Name: G patch domain-containing protein 4
• Protein Family: G patch domain-containing protein
• UniProt Gene Name: GPATCH4
• UniProt Synonym Gene Names: GPATC4
• UniProt Entry Name: GPTC4_HUMAN