Rabbit anti-Mouse Csnk1d Polyclonal Antibody | anti-Csnk1d antibody

Csnk1d, ID (Csnk1d, Hckid, Casein kinase I isoform delta, Tau-protein kinase CSNK1D) (PE)

Cat. Num. AAA6289362

• Gene Names: Csnk1d; AA409348; 1200006A05Rik; D930010H05Rik
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: Csnk1d; Polyclonal Antibody; ID (Csnk1d; Hckid; Casein kinase I isoform delta; Tau-protein kinase CSNK1D) (PE); Tau-protein kinase CSNK1D; anti-Csnk1d antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-Csnk1d antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Mouse Csnk1d antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-231 amino acids from the Central region of Mouse Csnk1d.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Mouse Csnk1d Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Csnk1d antibody detected the Csnk1d protein (arrow).)

Related Product Information for anti-Csnk1d antibody

This gene encodes a member of the casein kinase I (CKI) family of serine/threonine protein kinases. A highly similar human protein regulates an array of cellular processes by influencing the Wnt and hedgehog signaling pathways. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].

Product Categories/Family for anti-Csnk1d antibody

Antibodies; Protein Kinases

References

Sugiyama, Y., et al. Biochem. J. 427(3):489-497(2010). Etchegaray, J.P., et al. PLoS ONE 5 (4), E10303 (2010): Lee, H., et al. Proc. Natl. Acad. Sci. U.S.A. 106(50):21359-21364(2009). Martinez, G., et al. Invest. Ophthalmol. Vis. Sci. 50(10):4794-4806(2009). Isojima, Y., et al. Proc. Natl. Acad. Sci. U.S.A. 106(37):15744-15749(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 20544149
• NCBI GeneID: 104318
• NCBI Accession #: NP_620690.1
• NCBI GenBank Nucleotide #: NM_139059.2
• UniProt Accession #: Q9DC28; Q3TZK2; Q99KK4
• Molecular Weight: 46,818 Da
• NCBI Official Full Name: casein kinase I isoform delta isoform 1
• NCBI Official Synonym Full Names: casein kinase 1, delta
• NCBI Official Symbol: Csnk1d
• NCBI Official Synonym Symbols: AA409348; 1200006A05Rik; D930010H05Rik
• NCBI Protein Information: casein kinase I isoform delta; casein kinase I
• UniProt Protein Name: Casein kinase I isoform delta
• Protein Family: Casein kinase
• UniProt Gene Name: Csnk1d
• UniProt Synonym Gene Names: Hckid; CKI-delta; CKId

NCBI Description

This gene encodes a member of the casein kinase I (CKI) family of serine/threonine protein kinases. A highly similar human protein regulates an array of cellular processes by influencing the Wnt and hedgehog signaling pathways. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

CK1D: an ubiquitous protein kinase of the CK1 family. Enriched at the centrosomes in interphase and at the spindle during mitosis. May play a role in cell cycle progression. Two splice variant isoforms have been described.

Protein type: CK1 group; CK1 family; EC 2.7.11.1; EC 2.7.11.26; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 11|11 E2

Cellular Component: centrosome; cytoplasm; cytoskeleton; Golgi apparatus; membrane; neuron projection; nucleus; perinuclear region of cytoplasm; plasma membrane; spindle; spindle microtubule

Molecular Function: ATP binding; cadherin binding; kinase activity; nucleotide binding; peptide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; tau-protein kinase activity; transferase activity

Biological Process: circadian regulation of gene expression; endocytosis; Golgi organization and biogenesis; microtubule nucleation; non-motile cilium assembly; peptidyl-serine phosphorylation; phosphorylation; positive regulation of canonical Wnt signaling pathway; positive regulation of non-canonical Wnt signaling pathway; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of protein phosphorylation; positive regulation of Wnt receptor signaling pathway; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation; protein amino acid phosphorylation; protein localization to centrosome; protein localization to Golgi apparatus; regulation of cell shape; regulation of circadian rhythm; rhythmic process; spindle assembly; Wnt signaling pathway