Related Product Information for anti-CCL25 antibody
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9.
Product Categories/Family for anti-CCL25 antibody
References
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Wang, Y., et al. Cell. Mol. Immunol. 7(1):51-60(2010). Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010): Siezen, C.L., et al. Pediatr. Infect. Dis. J. 28(4):333-335(2009).
NCBI Description
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Uniprot Description
CCL25: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Belongs to the intercrine beta (chemokine CC) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: extracellular space; extracellular region
Molecular Function: chemokine activity; chemokine receptor binding; CCR10 chemokine receptor binding; hormone activity
Biological Process: G-protein coupled receptor protein signaling pathway; cell surface receptor linked signal transduction; immune response; chemotaxis; positive regulation of cell-matrix adhesion; inflammatory response; leukocyte migration
Product Notes
The CCL25 ccl25 (Catalog #
AAA6282048) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCL25, ID (CCL25, SCYA25, TECK, C-C motif chemokine 25, Chemokine TECK, Small-inducible cytokine A25, Thymus-expressed chemokine) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCL25 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CCL25 ccl25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"CCL25, Polyclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
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