Goat anti-Human Sarcoglycan, Gamma Polyclonal Antibody | anti-SGCG antibody
Sarcoglycan, Gamma (SGCG Sarcoglycan, Gamma (35kDa Dystrophin-Associated Glycoprotein))
Purified by peptide affinity chromatography.
Purified by peptide affinity chromatography.
Dilution: Peptide ELISA Titer: 1:2000
NCBI and Uniprot Product Information
NCBI Description
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq]
Uniprot Description
SGCG: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCG are the cause of limb-girdle muscular dystrophy type 2C (LGMD2C). LGMD2C is characterized by progressive muscle wasting from early childhood. Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Protein type: Dystrophin complex; Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q12
Cellular Component: cytoskeleton; cytoplasm; integral to membrane; plasma membrane; sarcoglycan complex; sarcolemma
Molecular Function: protein binding
Biological Process: cardiac muscle development; muscle development; heart contraction; muscle cell development
Disease: Muscular Dystrophy, Limb-girdle, Type 2c
Research Articles on SGCG
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Product Notes
The SGCG sgcg (Catalog #AAA627136) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Sarcoglycan, Gamma (SGCG Sarcoglycan, Gamma (35kDa Dystrophin-Associated Glycoprotein)) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Sarcoglycan, Gamma can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: Peptide ELISA Titer: 1:2000. Researchers should empirically determine the suitability of the SGCG sgcg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sarcoglycan, Gamma, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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