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Mouse SR Proteins Monoclonal Antibody

SR Proteins (Non-snRNP Splicing Factor) (MaxLight 750)

Reactivity
Canine, Chicken, Human, Mouse, Rabbit, Rat, Xenopus
Applications
Immunofluorescence, Western Blot
Purity
Purified by Protein A Affinity Chromatography
Synonyms
SR Proteins; Monoclonal Antibody; SR Proteins (Non-snRNP Splicing Factor) (MaxLight 750); anti-SR Proteins antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Canine, Chicken, Human, Mouse, Rabbit, Rat, Xenopus
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3G269
Specificity
Recognizes a sub-set of the non-snRNP splicing factors termed SR proteins. Detects SRp75, SRp55, SRp40 and SRp20 but not SRp30a or b (ASF/SF2, SC-35) proteins. Recognizes ~20 distinct nuclear proteins including the U1 70K component of the U1 snRNP and both subunits of U2AF1. Species Crossreactivity: chicken, human, mouse, rabbit, canine, rat, Xenopus. Reactivity has not been detected with yeasts.
Purity/Purification
Purified by Protein A Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight750.
Applicable Applications for anti-SR Proteins antibody
FLISA, Immunofluorescence (IF), Western Blot (WB)
Immunogen
Purified, de-phosphorylated bovine Srp55 and Drosophila p55-GST. The epitope has been mapped to a 40 amino acid polypeptide composed almost exclusively of arginine alternating with glutamate and aspartate.
Conjugate
MaxLight750
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-SR Proteins antibody
References
1. Neugebauer, KM, et al., J Cell Biol 129:899-908 (1995). 2. Tacke R and Manley JL, Proc Soc Exp Biol Med 220:59-63 (1999). 3. Graveley BR et al., Curr Biol 9:R6-7 (1999). 4. Fu X-D, Nature 365:82-85 (1993). 5. Zahler AM et al., Science 260:219-222 (1993). 6. Caceres JF, Science 265:1706-1709 (1994). 7. Kanopka A et al., Nature 393:185-7 (1998). 8. Misteli T et al., Nature 387:523-527 (1997).

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Product Notes

The SR Proteins (Catalog #AAA6259929) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SR Proteins (Non-snRNP Splicing Factor) (MaxLight 750) reacts with Canine, Chicken, Human, Mouse, Rabbit, Rat, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's SR Proteins can be used in a range of immunoassay formats including, but not limited to, FLISA, Immunofluorescence (IF), Western Blot (WB). Researchers should empirically determine the suitability of the SR Proteins for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SR Proteins, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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