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Testing Data
(Staining of human peripheral blood lymphocytes with C2259-12G1.)
Mouse CD8 Monoclonal Antibody | anti-CD8 antibody
CD8 (CD 8, CD8 Antigen alpha Polypeptide, Leu2 T Lymphocyte Antigen, MAL, OKT8 T Cell Antigen, p32, T Cell Antigen Leu2, T Cell Surface Glycoprotein CD8 alpha Chain) (FITC)
Reactivity
Human, Monkey
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation
Purity
Purified by ion exchange chromatography.
Synonyms
CD8; Monoclonal Antibody; CD8 (CD 8; CD8 Antigen alpha Polypeptide; Leu2 T Lymphocyte Antigen; MAL; OKT8 T Cell Antigen; p32; T Cell Antigen Leu2; T Cell Surface Glycoprotein CD8 alpha Chain) (FITC); anti-CD8 antibody
Host
Mouse
Reactivity
Human, Monkey
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H860
Specificity
Recognises the human CD8 cell surface glycoprotein expressed by a subset of peripheral blood T cells which express cytotoxic/suppressor activity. It is also expressed weakly on NK cells. Species Crossreactivity: marmoset, chimpanzee, Cynomolgus monkey, Red-bellied Tamarin
Purity/Purification
Purified by ion exchange chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
Applicable Applications for anti-CD8 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Immunogen
Normal human peripheral blood lymphocytes.
Conjugate
FITC
Preparation and Storage
Store at -20 degree C.
Testing Data
(Staining of human peripheral blood lymphocytes with C2259-12G1.)
Testing Data
(Staining of human peripheral blood lymphocytes with C2259-12G1.)
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Product Categories/Family for anti-CD8 antibody
References
1. Zarkesh-Esfahani, H. et al. (2001) High-dose Leptin activates human leukocytes via receptor expression on monocytes. J. Immunol. 167: 4593 - 4599. 2. Manninen, A. et al. (2002) HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells. J. Exp.Med. 195 (8): 1023 -1032. 3. Parnes, J.R. (1989) Molecular biology and function of CD4 and CD8. Adv. Immunol. 44: 265-311. 4. Kap, Y.S. et al. (2009) A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. J Histochem Cytochem. 57: 1159-67. 5. Hovden, A.O. et al. (2011) Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses. BMC Immunol. 12: 2. 6. Nelson, M. et al. (2010) Characterization of lethal inhalational infection with Francisella tularensis in the common marmoset (Callithrix jacchus). J Med Microbiol. 59: 1107-13. 7. Gibbings, D.J. et al. (2007) CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses. BMC Immunol. 8: 12. 8. Junker, A. et al. (2007) Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain. 130: 2789-99. 9. Held, K. et al. (2011) Expression of HSV-1 encoded miRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates. J Virol. Jul 27.
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Product Notes
The CD8 (Catalog #AAA6249716) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD8 (CD 8, CD8 Antigen alpha Polypeptide, Leu2 T Lymphocyte Antigen, MAL, OKT8 T Cell Antigen, p32, T Cell Antigen Leu2, T Cell Surface Glycoprotein CD8 alpha Chain) (FITC) reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's CD8 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CD8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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