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Western Blot (WB) (Western Blot Analysis: Rabbit Skeletal Muscle lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with MBS607629 (1.0ug/ml). Proteins were visualized using a IgG (HRP) goat anti-mouse secondary antibody and a chemiluminescence detection system. Arrow indicates protein Syntrophin (~58kD).)

Mouse Syntrophin Monoclonal Antibody | anti-SNTB1 antibody

Syntrophin (dystrophin-associated protein A1, 59kD, basic component 1, 59-DAP, 59kD dystrophin-associated protein A1 basic component 1, A1B, Beta-1-syntrophin, BSYN2, DAPA1B, FLJ22442, MGC111389, SNT2, SNT2B1, Syntrophin-2, Tax interaction protein 43, TIP

Gene Names
SNTB1; A1B; SNT2; BSYN2; 59-DAP; DAPA1B; SNT2B1; TIP-43
Reactivity
Human, Mouse, Rabbit, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
Syntrophin; Monoclonal Antibody; Syntrophin (dystrophin-associated protein A1; 59kD; basic component 1; 59-DAP; 59kD dystrophin-associated protein A1 basic component 1; A1B; Beta-1-syntrophin; BSYN2; DAPA1B; FLJ22442; MGC111389; SNT2; SNT2B1; Syntrophin-2; Tax interaction protein 43; TIP; anti-SNTB1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rabbit, Rat
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
9H279
Specificity
Recognizes Syntrophin, Mr ~58kD. Species Crossreactivity: human, rabbit, mouse, rat and Torpedo.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-SNTB1 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane (Q13884, NM_021021.3). Cellular Localization: Cell membrane, sarcolemma.
Conjugate
Biotin
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western Blot Analysis: Rabbit Skeletal Muscle lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with MBS607629 (1.0ug/ml). Proteins were visualized using a IgG (HRP) goat anti-mouse secondary antibody and a chemiluminescence detection system. Arrow indicates protein Syntrophin (~58kD).)

Western Blot (WB) (Western Blot Analysis: Rabbit Skeletal Muscle lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with MBS607629 (1.0ug/ml). Proteins were visualized using a IgG (HRP) goat anti-mouse secondary antibody and a chemiluminescence detection system. Arrow indicates protein Syntrophin (~58kD).)
Product Categories/Family for anti-SNTB1 antibody
References
1. Adams, M., et al. (2006) Experimental Cell Research. 312: 3084-3095 2. Solimena, M., et al. (2001) EMBO Journal. 20: 4013:4023 3. Froehner, S. (1984). J. Cell Bio. 99: 88-96.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58,061 Da
NCBI Official Full Name
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
NCBI Official Synonym Full Names
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
NCBI Official Symbol
SNTB1
NCBI Official Synonym Symbols
A1B; SNT2; BSYN2; 59-DAP; DAPA1B; SNT2B1; TIP-43
NCBI Protein Information
beta-1-syntrophin; syntrophin-2; tax interaction protein 43; 59 kDa dystrophin-associated protein A1 basic component 1; dystrophin-associated protein A1, 59kD, basic component 1
UniProt Protein Name
Beta-1-syntrophin
Protein Family
UniProt Gene Name
SNTB1
UniProt Synonym Gene Names
SNT2B1; DAPA1B; TIP-43
UniProt Entry Name
SNTB1_HUMAN

NCBI Description

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]

Uniprot Description

SNTB1: Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. Belongs to the syntrophin family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 8q23-q24

Cellular Component: dystrophin-associated glycoprotein complex; protein complex; focal adhesion; cytoskeleton; cytoplasm; synapse; sarcolemma

Molecular Function: calmodulin binding; protein binding; actin binding; PDZ domain binding

Biological Process: muscle contraction

Research Articles on SNTB1

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Product Notes

The SNTB1 sntb1 (Catalog #AAA6242994) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Syntrophin (dystrophin-associated protein A1, 59kD, basic component 1, 59-DAP, 59kD dystrophin-associated protein A1 basic component 1, A1B, Beta-1-syntrophin, BSYN2, DAPA1B, FLJ22442, MGC111389, SNT2, SNT2B1, Syntrophin-2, Tax interaction protein 43, TIP reacts with Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Syntrophin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the SNTB1 sntb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syntrophin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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