Chemiluminescence
(HEK293 lysate (10ug protein in RIPA buffer) over-expressing human UCN3 with DYKDDDDK tag probed with MBS622718 (1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed with MBS622718 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detection by chemiluminescence.)
Goat Urocortin 3 Polyclonal Antibody | anti-UCN3 antibody
Urocortin 3 (UCN3, Stresscopin, MGC119002, SCP, SPC, UCNIII)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Peptide ELISA: 1:16,000
Chemiluminescence
(HEK293 lysate (10ug protein in RIPA buffer) over-expressing human UCN3 with DYKDDDDK tag probed with MBS622718 (1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed with MBS622718 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detection by chemiluminescence.)
Chemiluminescence
(HEK293 lysate (10ug protein in RIPA buffer) over-expressing human UCN3 with DYKDDDDK tag probed with MBS622718 (1ug/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed with MBS622718 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detection by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq]
Uniprot Description
UCN3: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10p15.1
Cellular Component: extracellular space; nerve terminal
Molecular Function: G-protein-coupled receptor binding; hormone activity; corticotropin-releasing hormone receptor 2 binding
Biological Process: response to starvation; cellular response to nutrient levels; digestion; response to glucose stimulus; positive regulation of insulin secretion; positive regulation of membrane potential; G-protein signaling, adenylate cyclase activating pathway; response to corticosterone stimulus
Research Articles on UCN3
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Product Notes
The UCN3 ucn3 (Catalog #AAA622718) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Urocortin 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: Peptide ELISA: 1:16,000. Researchers should empirically determine the suitability of the UCN3 ucn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Urocortin 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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