Goat Phosphatidylinositol transfer protein Polyclonal Antibody | anti-PITPNB antibody
Phosphatidylinositol transfer protein (PITPN, PITPNB, phosphotidylinositol transfer protein, phosphatidylinositol transfer protein, PITP alpha)
Gene Names
PITPNB; VIB1B; PtdInsTP; PI-TP-beta; PITPNB
Reactivity
Human, Mouse, Rabbit, Rat
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Phosphatidylinositol transfer protein; Polyclonal Antibody; Phosphatidylinositol transfer protein (PITPN; PITPNB; phosphotidylinositol transfer protein; phosphatidylinositol transfer protein; PITP alpha); Anti -Phosphatidylinositol transfer protein (PITPN; anti-PITPNB antibody
Host
Goat
Reactivity
Human, Mouse, Rabbit, Rat
Clonality
Polyclonal
Specificity
Recognizes Human, Mouse, Rat, Rabbit PITPN. Species Crossreactivity: human, mouse, rat, rabbit.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Applicable Applications for anti-PITPNB antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Approx 32kD band observed in 293 and Human Liver lysates (predicted MW of 31kD according to NP_006215). Recommended for use at 1-3ug/ml., Staining (1ug/ml) of 293 lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Optimal dilutions to be determined by the researcher.
Immunogen
C-RQKDPVKGMTADD, C Terminus
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Product Categories/Family for anti-PITPNB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
31,540 Da
NCBI Official Full Name
phosphatidylinositol transfer protein
NCBI Official Synonym Full Names
phosphatidylinositol transfer protein, beta
NCBI Official Symbol
PITPNB
NCBI Official Synonym Symbols
VIB1B; PtdInsTP; PI-TP-beta; PITPNB
NCBI Protein Information
phosphatidylinositol transfer protein beta isoform; ptdInsTP beta; PtdIns transfer protein beta; phosphotidylinositol transfer protein, beta
UniProt Protein Name
Phosphatidylinositol transfer protein beta isoform
Protein Family
UniProt Gene Name
PITPNB
UniProt Entry Name
PIPNB_HUMAN
NCBI Description
The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. [provided by RefSeq]
Uniprot Description
PITPNB: transfers phosphatidylinositol, phosphatidylcholine and sphingomyelin between membrane bilayers. Associates mainly with the trans-Golgi network. Ser-261 is constitutively phosphorylated.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 22q12.1
Cellular Component: Golgi membrane; endoplasmic reticulum membrane
Molecular Function: lipid binding
Biological Process: in utero embryonic development; phospholipid metabolic process; glycerophospholipid biosynthetic process; phospholipid transport; lipid metabolic process
Research Articles on PITPNB
1. Phosphatidylinositol and phosphatidylcholine exchange activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.
2. The presence of PITPbeta splice variants adds an extra level of proteome complexity
3. Role of PITPNB- not required for sphingomyelin trafficking
2. The presence of PITPbeta splice variants adds an extra level of proteome complexity
3. Role of PITPNB- not required for sphingomyelin trafficking
Similar Products
Product Notes
The PITPNB pitpnb (Catalog #AAA619502) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Phosphatidylinositol transfer protein (PITPN, PITPNB, phosphotidylinositol transfer protein, phosphatidylinositol transfer protein, PITP alpha) reacts with Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Phosphatidylinositol transfer protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Approx 32kD band observed in 293 and Human Liver lysates (predicted MW of 31kD according to NP_006215). Recommended for use at 1-3ug/ml., Staining (1ug/ml) of 293 lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the PITPNB pitpnb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phosphatidylinositol transfer protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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