Mouse HERPUD1 Monoclonal Antibody | anti-HERPUD1 antibody

HERPUD1 (homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-like Domain Member 1, HERP, KIAA0025, Mif1, SUP) (FITC)

Cat. Num. AAA6178082

• Gene Names: HERPUD1; SUP; HERP; Mif1
• Applications: Western Blot
• Purity: Purified
• Synonyms: HERPUD1; Monoclonal Antibody; HERPUD1 (homocysteine-Inducible; Endoplasmic Reticulum Stress-Inducible; Ubiquitin-like Domain Member 1; HERP; KIAA0025; Mif1; SUP) (FITC); homocysteine-Inducible; SUP; anti-HERPUD1 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 2F4
• Specificity: Recognizes HERPUD1.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
• Sequence Length: 391

• Applicable Applications for anti-HERPUD1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: HERPUD1 (AAH32673, 1aa-391aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN
• Conjugate: FITC
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.; ; FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Testing Data

(Detection limit for recombinant GST tagged HERPUD1 is 0.3 ng/ml as a capture antibody.)

Related Product Information for anti-HERPUD1 antibody

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq]

Product Categories/Family for anti-HERPUD1 antibody

Antibodies; Ubiquitin

NCBI and Uniprot Product Information

• NCBI GI #: 21619177
• NCBI GeneID: 9709
• NCBI Official Full Name: Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
• NCBI Official Synonym Full Names: homocysteine inducible ER protein with ubiquitin like domain 1
• NCBI Official Symbol: HERPUD1
• NCBI Official Synonym Symbols: SUP; HERP; Mif1
• NCBI Protein Information: homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
• Protein Family: Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

NCBI Description

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]