Mouse anti-Human TRAPPC2 Monoclonal Antibody | anti-TRAPPC2 antibody

TRAPPC2 (Trafficking Protein Particle Complex Subunit 2, Sedlin, SEDL) (HRP)

Cat. Num. AAA6155511

• Gene Names: TRAPPC2; SEDL; SEDT; MIP2A; TRS20; ZNF547L; hYP38334; TRAPPC2P1
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TRAPPC2; Monoclonal Antibody; TRAPPC2 (Trafficking Protein Particle Complex Subunit 2; Sedlin; SEDL) (HRP); anti-TRAPPC2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 2E10
• Specificity: Recognizes human TRAPPC2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
• Sequence Length: 2036

• Applicable Applications for anti-TRAPPC2 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-141 from human TRAPPC2 (AAH16915) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSPIRSSAFDRKVQFLGKKHLLS*
• Conjugate: HRP
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (41.51kD).)

Western Blot (WB)

(TRAPPC2 monoclonal antibody, Western Blot analysis of TRAPPC2 expression in Hela.)

Testing Data

(Detection limit for recombinant GST tagged TRAPPC2 is ~0.3ng/ml as a capture antibody.)

Related Product Information for anti-TRAPPC2 antibody

Prevents transcriptional repression and induction of cell death by ENO1. May play a role in vesicular transport from endoplasmic reticulum to Golgi.

Product Categories/Family for anti-TRAPPC2 antibody

Antibodies; Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 16877317
• NCBI GeneID: 6399
• NCBI Official Full Name: Homo sapiens trafficking protein particle complex 2, mRNA
• NCBI Official Synonym Full Names: trafficking protein particle complex 2
• NCBI Official Symbol: TRAPPC2
• NCBI Official Synonym Symbols: SEDL; SEDT; MIP2A; TRS20; ZNF547L; hYP38334; TRAPPC2P1
• NCBI Protein Information: trafficking protein particle complex subunit 2
• Protein Family: Trafficking protein particle complex

NCBI Description

The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]