Western Blot (WB)
(Western Blot of MBS615171 in human brain membrane fraction.)
Rabbit anti-Human, Mouse ANKTM1 Polyclonal Antibody
ANKTM1 (TRPA1, Transient Receptor Potential Cation Channel, subfamily A, Member 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, Transient receptor potential cation channel subfamily A member 1)
Purified by affinity chromatography.
Purified by affinity chromatography.
Dilution: Western Blot: 2ug/ml. Detects a band at ~110kD.
Immunocytochemistry (IF): 1:200
Immunohistochemistry (Paraffin): 1:100-1:250
Immunohistochemistry: 0.5-1ug/ml
Western Blot (WB)
(Western Blot of MBS615171 in human brain membrane fraction.)
Western Blot (WB)
(Western Blot of MBS615171 in human brain membrane fraction.)
NCBI and Uniprot Product Information
Uniprot Description
TRPA1: Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)- tetrahydrocannabinol (THC), the psychoactive component of marijuana. Not involved in menthol sensation. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system. Belongs to the transient receptor (TC 1.A.4) family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: stereocilium bundle; membrane; integral to membrane
Molecular Function: channel activity; calcium channel activity; ion channel activity
Biological Process: response to drug; detection of chemical stimulus involved in sensory perception of pain; detection of mechanical stimulus involved in sensory perception of pain; response to hydrogen peroxide; transport; calcium ion transport; response to stimulus; response to pain; ion transport; response to cold; thermoception
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Product Notes
The ANKTM1 (Catalog #AAA615171) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ANKTM1 (TRPA1, Transient Receptor Potential Cation Channel, subfamily A, Member 1, Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, Transient receptor potential cation channel subfamily A member 1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ANKTM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC). Suitable for use in Western Blot, Immunocytochemistry and Immunohistochemistry. Dilution: Western Blot: 2ug/ml. Detects a band at ~110kD. Immunocytochemistry (IF): 1:200 Immunohistochemistry (Paraffin): 1:100-1:250 Immunohistochemistry: 0.5-1ug/ml. Researchers should empirically determine the suitability of the ANKTM1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANKTM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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