Rabbit anti-Human Kallikrein L4 Polyclonal Antibody | anti-KLK13 antibody

Kallikrein L4 (KLK L4)

Cat. Num. AAA614978

• Gene Names: KLK13; KLKL4; KLK-L4
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Kallikrein L4; Polyclonal Antibody; Kallikrein L4 (KLK L4); Anti -Kallikrein L4 (KLK L4); anti-KLK13 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Reacts with residues 262-277 [IRKYETQQQKWLKGPQ] of the human KLK-L4 protein.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide before the addition of 40% glycerol.

• Applicable Applications for anti-KLK13 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.; Dilution: Western Blot: 1:250-1:500
• Immunogen: Synthetic peptide, aa262-277 [IRKYETQQQKWLKGPQ] of the human KLK-L4 protein.
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-KLK13 antibody

Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. The novel KLK gene, KLK-L4, is expressed in a variety of tissues including prostate, salivary gland, breast, and testis. Its expression is regulated by steroid hormones in breast cancer cell lines may be involved in the pathogenesis and/or progression of breast cancer.

Product Categories/Family for anti-KLK13 antibody

Antibodies; Abs to Kallikrein

NCBI and Uniprot Product Information

• NCBI GI #: 11496281
• NCBI GeneID: 26085
• NCBI Accession #: NP_056411.1
• NCBI GenBank Nucleotide #: NM_015596.1
• UniProt Accession #: Q9UKR3; Q9Y433; A7UNK6
• Molecular Weight: 30,570 Da
• NCBI Official Full Name: kallikrein-13
• NCBI Official Synonym Full Names: kallikrein-related peptidase 13
• NCBI Official Symbol: KLK13
• NCBI Official Synonym Symbols: KLKL4; KLK-L4
• NCBI Protein Information: kallikrein-13; kallikrein 13; kallikrein-like gene 4; kallikrein-like protein 4
• UniProt Protein Name: Kallikrein-13
• Protein Family: Kallikrein
• UniProt Gene Name: KLK13
• UniProt Synonym Gene Names: KLKL4; KLK-L4
• UniProt Entry Name: KLK13_HUMAN

NCBI Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

KLK13: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

Protein type: Protease; EC 3.4.21.-; Secreted, signal peptide; Vesicle; Secreted

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space; cytoplasm; extracellular region; secretory granule

Molecular Function: protein binding; hydrolase activity; serine-type endopeptidase activity

Biological Process: protein processing; proteolysis