Rabbit a-Tocopherol Polyclonal Antibody | anti-Ttpa antibody
a-Tocopherol (Vitamin E), Conjugated
Antiserum previously preabsobed on protein carriers, and purified by ammonium sulfate precipitation and gel filtration.
Antiserum previously preabsobed on protein carriers, and purified by ammonium sulfate precipitation and gel filtration.
Dilution: Immunohistochemistry: 1:500-1:2000
NCBI and Uniprot Product Information
NCBI Description
binds the vitamin tocopherol and enhances its transfer between separate membranes [RGD, Feb 2006]
Uniprot Description
TTPA: Binds alpha-tocopherol and enhances its transfer between separate membranes. Defects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED). AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E.
Protein type: Transporter
Cellular Component: late endosome; cytosol
Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; transporter activity; vitamin binding; phosphatidylinositol-3,4-bisphosphate binding; vitamin E binding
Biological Process: vitamin E metabolic process; embryonic placenta development; response to toxin; intracellular pH reduction; intermembrane transport; vitamin transport; developmental process; response to nutrient; response to pH; placenta development
Research Articles on Ttpa
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Product Notes
The Ttpa ttpa (Catalog #AAA612102) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's a-Tocopherol can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC). Suitable for use in ELISA and Immunohistochemistry. Dilution: Immunohistochemistry: 1:500-1:2000. Researchers should empirically determine the suitability of the Ttpa ttpa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "a-Tocopherol, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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