Mouse anti-Human CDR2 Monoclonal Antibody | anti-CDR2 antibody
CDR2 (Cerebellar Degeneration-related Protein 2, Paraneoplastic Cerebellar Degeneration-associated Antigen, Major Yo Paraneoplastic Antigen, PCD17)
Gene Names
CDR2; Yo; CDR62
Reactivity
Human
Applications
ELISA, Western Blot, Immunofluorescence
Purity
PurifiedPurified.
Synonyms
CDR2; Monoclonal Antibody; CDR2 (Cerebellar Degeneration-related Protein 2; Paraneoplastic Cerebellar Degeneration-associated Antigen; Major Yo Paraneoplastic Antigen; PCD17); Anti -CDR2 (Cerebellar Degeneration-related Protein 2; anti-CDR2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a, k
Clone Number
4F5
Specificity
Recognizes human CDR2.
Purity/Purification
Purified
Purified.
Purified.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Applicable Applications for anti-CDR2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
Suitable for use in ELISA, Immunofluorescence, and Western Blot.
Immunogen
CDR2 (NP_001793, 296-405aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-CDR2 antibody
CDR2 (Cerebellar degeneration related protein 2) is an onconeuronal antigen; i.e. an antigen that is expressed by systemic tumors and elicits an immune response that may develop into an autoimmune neuronal degeneration. Paraneoplastic cerebellar degeneration (PCD) is a disorder in which breast or ovarian tumors express CDR2, which normally is expressed in cerebellar Purkinje neurons. Patients with PCD carry a characteristic antibody called anti-Yo. Anti-Yo sera reacts with at least 2 antigens, a major species CDR2, and a minor species CDR1.
Product Categories/Family for anti-CDR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,855 Da
NCBI Official Full Name
cerebellar degeneration-related protein 2
NCBI Official Synonym Full Names
cerebellar degeneration-related protein 2, 62kDa
NCBI Official Symbol
CDR2
NCBI Official Synonym Symbols
Yo; CDR62
NCBI Protein Information
cerebellar degeneration-related protein 2; Yo paraneoplastic antigen; major Yo paraneoplastic antigen; paraneoplastic cerebellar degeneration-associated antigen
UniProt Protein Name
Cerebellar degeneration-related protein 2
Protein Family
UniProt Gene Name
CDR2
UniProt Synonym Gene Names
PCD17
UniProt Entry Name
CDR2_HUMAN
Uniprot Description
CDR2: Belongs to the CDR2 family.
Chromosomal Location of Human Ortholog: 16p12.3
Cellular Component: cytoplasm
Molecular Function: protein binding
Research Articles on CDR2
Similar Products
Product Notes
The CDR2 cdr2 (Catalog #AAA609860) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CDR2 (Cerebellar Degeneration-related Protein 2, Paraneoplastic Cerebellar Degeneration-associated Antigen, Major Yo Paraneoplastic Antigen, PCD17) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF). Suitable for use in ELISA, Immunofluorescence, and Western Blot. Researchers should empirically determine the suitability of the CDR2 cdr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDR2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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