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Mouse anti-Human Orexin 2 Receptor Monoclonal Antibody | anti-HCRTR2 antibody

Orexin 2 Receptor (Orexin Receptor 2, Orexin Receptor-2, OX2R, CD200 Cell Surface Glycoprotein Receptor, CD200 Receptor 1, CD200R1, CD200R, Cell Surface Glycoprotein CD200 Receptor 1, Cell Surface Glycoprotein OX2 Receptor 1, CRTR2, Hypocretin 2 Receptor,

Gene Names
HCRTR2; OX2R
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Purified
Purified
Synonyms
Orexin 2 Receptor; Monoclonal Antibody; Orexin 2 Receptor (Orexin Receptor 2; Orexin Receptor-2; OX2R; CD200 Cell Surface Glycoprotein Receptor; CD200 Receptor 1; CD200R1; CD200R; Cell Surface Glycoprotein CD200 Receptor 1; Cell Surface Glycoprotein OX2 Receptor 1; CRTR2; Hypocretin 2 Receptor; ; Anti -Orexin 2 Receptor (Orexin Receptor 2; anti-HCRTR2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
OX108
Specificity
Recognizes human CD200R.
Purity/Purification
Purified
Purified
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide, 1% BSA. Labeled with FITC.
Applicable Applications for anti-HCRTR2 antibody
Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: 10ul labels of a neat working dilution to 10e6 cells in 100ul.
Immunogen
Human CD200R.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Related Product Information for anti-HCRTR2 antibody
In humans CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leukocytes including T-lymphocytes and mast cells (1). Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function.
Product Categories/Family for anti-HCRTR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,694 Da
NCBI Official Full Name
orexin receptor type 2
NCBI Official Synonym Full Names
hypocretin (orexin) receptor 2
NCBI Official Symbol
HCRTR2
NCBI Official Synonym Symbols
OX2R
NCBI Protein Information
orexin receptor type 2; ox2-R; ox-2-R; orexin type-2 receptor; hypocretin receptor type 2
UniProt Protein Name
Orexin receptor type 2
Protein Family
UniProt Gene Name
HCRTR2
UniProt Synonym Gene Names
Ox-2-R; Ox2-R; Ox2R
UniProt Entry Name
OX2R_HUMAN

NCBI Description

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]

Uniprot Description

HCRTR2: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: neuropeptide receptor activity; orexin receptor activity; peptide hormone binding; peptide binding

Biological Process: synaptic transmission; neuropeptide signaling pathway; circadian sleep/wake cycle process; feeding behavior; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); cellular response to hormone stimulus; regulation of circadian sleep/wake cycle, sleep

Research Articles on HCRTR2

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Product Notes

The HCRTR2 hcrtr2 (Catalog #AAA609074) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Orexin 2 Receptor (Orexin Receptor 2, Orexin Receptor-2, OX2R, CD200 Cell Surface Glycoprotein Receptor, CD200 Receptor 1, CD200R1, CD200R, Cell Surface Glycoprotein CD200 Receptor 1, Cell Surface Glycoprotein OX2 Receptor 1, CRTR2, Hypocretin 2 Receptor, reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Orexin 2 Receptor can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry. Dilution: Flow Cytometry: 10ul labels of a neat working dilution to 10e6 cells in 100ul. Researchers should empirically determine the suitability of the HCRTR2 hcrtr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Orexin 2 Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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