Testing Data
(Rat Peritoneal Macrophages stained with MBS606855.)
Mouse CD200 Receptor 1, Low Endotoxin Monoclonal Antibody | anti-CD200 antibody
CD200 Receptor 1, Low Endotoxin (Cd200r1, Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor, Cell Surface Glycoprotein OX2 Receptor 1, Mox2r, OX102 Antigen, Ox2r)
Gene Names
CD200; MRC; MOX1; MOX2; OX-2
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein G Chromatography. Endotoxin: 0.01EU/ug.
Synonyms
CD200 Receptor 1; Low Endotoxin; Monoclonal Antibody; Low Endotoxin (Cd200r1; Cell Surface Glycoprotein CD200 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; Cell Surface Glycoprotein OX2 Receptor 1; Mox2r; OX102 Antigen; Ox2r); Anti -CD200 Receptor 1; anti-CD200 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H1966
Specificity
Recognizes the rat OX2 (CD200) ligand. This antigen is a heavily glycosylated 60-100kD cell surface molecule expressed by cells of the myeloid lineage but not by T or B lymphocytes.
Purity/Purification
Affinity Purified
Purified by Protein G Chromatography. Endotoxin: 0.01EU/ug.
Purified by Protein G Chromatography. Endotoxin: 0.01EU/ug.
Form/Format
Supplied as a liquid in PBS.
Applicable Applications for anti-CD200 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry.
Dilution: Immunohistochemistry Frozen: 1:10-1:200, 10ul labels 1x10e6 cells in 100ul.
Dilution: Immunohistochemistry Frozen: 1:10-1:200, 10ul labels 1x10e6 cells in 100ul.
Immunogen
Membrane fraction of thioglycollate-elicited rat peripheral cells.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Testing Data
(Rat Peritoneal Macrophages stained with MBS606855.)
Testing Data
(Rat Peritoneal Macrophages stained with MBS606855.)
Related Product Information for anti-CD200 antibody
CD200 is expressed by a subset of B lymphocytes, some endothelial cells and by neurons. Recent studies have suggested that the CD200-CD200 ligand system is of importance in the control of macrophage and granulocyte activation.
Product Categories/Family for anti-CD200 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
CD200 antigen, isoform CRA_a
NCBI Official Synonym Full Names
CD200 molecule
NCBI Official Symbol
CD200
NCBI Official Synonym Symbols
MRC; MOX1; MOX2; OX-2
NCBI Protein Information
OX-2 membrane glycoprotein; CD200 antigen; MRC OX-2 antigen; OTTHUMP00000214500; OTTHUMP00000214501; OTTHUMP00000214502; antigen identified by monoclonal antibody MRC OX-2
UniProt Protein Name
OX-2 membrane glycoprotein
Protein Family
UniProt Entry Name
OX2G_HUMAN
NCBI Description
The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq]
Uniprot Description
CD200: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q13.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding
Biological Process: regulation of immune response
Research Articles on CD200
Similar Products
Product Notes
The CD200 (Catalog #AAA606855) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD200 Receptor 1, Low Endotoxin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry. Dilution: Immunohistochemistry Frozen: 1:10-1:200, 10ul labels 1x10e6 cells in 100ul. Researchers should empirically determine the suitability of the CD200 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD200 Receptor 1, Low Endotoxin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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