Rabbit anti-Human PGM3 Polyclonal Antibody | anti-PGM3 antibody

PGM3, ID (PGM3, AGM1, Phosphoacetylglucosamine mutase, Acetylglucosamine phosphomutase, N-acetylglucosamine-phosphate mutase, Phosphoglucomutase-3)

Cat. Num. AAA6013631

• Gene Names: PGM3; AGM1; PAGM; PGM 3
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: PGM3; Polyclonal Antibody; ID (PGM3; AGM1; Phosphoacetylglucosamine mutase; Acetylglucosamine phosphomutase; N-acetylglucosamine-phosphate mutase; Phosphoglucomutase-3); Anti -PGM3; anti-PGM3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-PGM3 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: PGM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 236-263 amino acids selected from the Central region of human PGM3.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PGM3 Antibody (Center) western blot analysis in Uterus tissue lysates (35ug/lane).This demonstrates the PGM3 antibody detected the PGM3 protein (arrow).)

Related Product Information for anti-PGM3 antibody

PGM3 interconverts GlcNAc-6-P and GlcNAc-1-P.

Product Categories/Family for anti-PGM3 antibody

Antibodies; Abs to Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 7661568
• NCBI GeneID: 5238
• NCBI Accession #: NP_056414.1
• NCBI GenBank Nucleotide #: NM_015599.2
• UniProt Accession #: O95394; Q5JWR4; Q96J46; Q9H8G5; Q9NS94; Q9NTT6; Q9UFV5; B2RB65; B4DX94; D6RF12; E1P547; E9PF86
• Molecular Weight: 59,852 Da
• NCBI Official Full Name: phosphoacetylglucosamine mutase isoform 2
• NCBI Official Synonym Full Names: phosphoglucomutase 3
• NCBI Official Symbol: PGM3
• NCBI Official Synonym Symbols: AGM1; PAGM; PGM 3
• NCBI Protein Information: phosphoacetylglucosamine mutase; acetylglucosamine phosphomutase; N-acetylglucosamine-phosphate mutase 1
• UniProt Protein Name: Phosphoacetylglucosamine mutase
• UniProt Gene Name: PGM3
• UniProt Synonym Gene Names: AGM1; PAGM; PGM 3
• UniProt Entry Name: AGM1_HUMAN

NCBI Description

This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

PGM3: Interconverts GlcNAc-6-P and GlcNAc-1-P. Belongs to the phosphohexose mutase family.

Protein type: EC 5.4.2.3; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Isomerase

Chromosomal Location of Human Ortholog: 6q14.1-q15

Cellular Component: cytosol

Molecular Function: phosphoglucomutase activity; magnesium ion binding; phosphoacetylglucosamine mutase activity

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation; UDP-N-acetylglucosamine biosynthetic process; hemopoiesis; spermatogenesis; protein amino acid N-linked glycosylation via asparagine; glucose 1-phosphate metabolic process; post-translational protein modification; glucosamine metabolic process

Disease: Immunodeficiency 23