Rabbit anti-Human GNPDA1 Polyclonal Antibody | anti-GNPDA1 antibody

GNPDA1, CT (Glucosamine-6-phosphate Deaminase 1, Glucosamine-6-phosphate Isomerase 1, GlcN6P Deaminase 1, Oscillin, GNPI, HLN, KIAA0060)

Cat. Num. AAA6013263

• Gene Names: GNPDA1; GNPI
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: GNPDA1; Polyclonal Antibody; CT (Glucosamine-6-phosphate Deaminase 1; Glucosamine-6-phosphate Isomerase 1; GlcN6P Deaminase 1; Oscillin; GNPI; HLN; KIAA0060); Anti -GNPDA1; anti-GNPDA1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human GNPDA1. Species sequence homology: mouse and rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.02% sodium azide.

• Applicable Applications for anti-GNPDA1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
• Application Notes: Suitable for use in ELISA, Immunocytochemistry, Western Blot and Immunohistochemistry.; Dilution: Western Blot: 1-2ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
• Immunogen: Synthetic peptide corresponding to 18aa from human GNPDA1 at C-terminus.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of GNPDA1 in mouse kidney lysate with GNPDA1 antibody at (A) 1 and (B) 2ug/ml.)

Related Product Information for anti-GNPDA1 antibody

Glucosamine-6-phosphate deaminase (GNPDA) catalyzes the conversion of glucosamine-6-phosphate to fructose-6-phosphate, a reaction that under physiological conditions proceeds to the formation of fructose-6-phosphate. GNPDA is the sole enzyme linking hexosamine systems with glycolytic pathways, and has been proposed to provide a source of energy in the form of phosphosugar derived from the catabolism of hexosamines found in glycoproteins, glycolipids, and sialic acid-containing macromolecules. GNPDA localizes close to the developing acrosome vesicle and in spermatozoa close to the acrosomal region, and may play a role in the acrosome reaction.

Product Categories/Family for anti-GNPDA1 antibody

Antibodies; Abs to Enzymes; Isomerase

NCBI and Uniprot Product Information

• NCBI GI #: 136255753
• NCBI GeneID: 522919
• NCBI Accession #: NP_001073756.2
• NCBI GenBank Nucleotide #: NM_001080287.3
• UniProt Accession #: A4FV08
• Molecular Weight: 32,580 Da
• NCBI Official Full Name: glucosamine-6-phosphate isomerase 1
• NCBI Official Synonym Full Names: glucosamine-6-phosphate deaminase 1<
• NCBI Official Symbol: GNPDA1
• NCBI Official Synonym Symbols: GNPI
• NCBI Protein Information: glucosamine-6-phosphate isomerase 1; GNPDA 1; oscillin; glcN6P deaminase 1
• UniProt Protein Name: Glucosamine-6-phosphate isomerase 1
• Protein Family: Glucosamine-6-phosphate isomerase
• UniProt Gene Name: GNPDA1
• UniProt Synonym Gene Names: GNPDA 1
• UniProt Entry Name: GNPI1_BOVIN

Uniprot Description

Function: Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo

By similarity.

Catalytic activity: D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3.

Subunit structure: Homohexamer

By similarity.

Subcellular location: Cytoplasm

By similarity.

Sequence similarities: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.