Rabbit anti-Human NAPSA Polyclonal Antibody | anti-NAPSA antibody

NAPSA, CT (NAPSA, NAP1, NAPA, Napsin-A, Aspartyl protease 4, Napsin-1, TA01/TA02)

Cat. Num. AAA6012268

• Gene Names: NAPSA; KAP; Kdap; NAP1; NAPA; SNAPA
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: NAPSA; Polyclonal Antibody; CT (NAPSA; NAP1; NAPA; Napsin-A; Aspartyl protease 4; Napsin-1; TA01/TA02); Anti -NAPSA; anti-NAPSA antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-NAPSA antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:10-50
• Immunogen: NAPSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-397 amino acids from the C-terminal region of human NAPSA.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(NAPSA Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NAPSA antibody detected the NAPSA protein (arrow).)

Immunohistochemistry (IHC)

(NAPSA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NAPSA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-NAPSA antibody

The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq].

Product Categories/Family for anti-NAPSA antibody

Antibodies; Abs to Enzymes; Protease (Proteinase; Peptidase)

NCBI and Uniprot Product Information

• NCBI GI #: 4758754
• NCBI GeneID: 9476
• NCBI Accession #: NP_004842.1
• NCBI GenBank Nucleotide #: NM_004851.1
• UniProt Accession #: O96009; Q8WWD9
• Molecular Weight: 45,387 Da
• NCBI Official Full Name: napsin-A preproprotein
• NCBI Official Synonym Full Names: napsin A aspartic peptidase
• NCBI Official Symbol: NAPSA
• NCBI Official Synonym Symbols: KAP; Kdap; NAP1; NAPA; SNAPA
• NCBI Protein Information: napsin-A; ASP4; asp 4; napsin-1; TA01/TA02; pronapsin A; aspartyl protease 4; kidney-derived aspartic protease-like protein
• UniProt Protein Name: Napsin-A
• Protein Family: Napsin
• UniProt Gene Name: NAPSA
• UniProt Synonym Gene Names: NAP1; NAPA; ASP4; Asp 4
• UniProt Entry Name: NAPSA_HUMAN

NCBI Description

The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq, Jul 2008]

Uniprot Description

NAPSA: May be involved in processing of pneumocyte surfactant precursors. Belongs to the peptidase A1 family.

Protein type: EC 3.4.23.-; Secreted; Secreted, signal peptide; Protease

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space; lysosome

Molecular Function: peptidase activity; endopeptidase activity; aspartic-type endopeptidase activity

Biological Process: membrane protein proteolysis; proteolysis; surfactant homeostasis