Mouse anti-Human FGD6 Polyclonal Antibody | anti-FGD6 antibody

FGD6 (KIAA1362, ZFYVE24, FYVE, RhoGEF and PH Domain-containing Protein 6, Zinc Finger FYVE Domain-containing Protein 24, FLJ11183)

Cat. Num. AAA6012071

• Gene Names: FGD6; ZFYVE24
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: FGD6; Polyclonal Antibody; FGD6 (KIAA1362; ZFYVE24; FYVE; RhoGEF and PH Domain-containing Protein 6; Zinc Finger FYVE Domain-containing Protein 24; FLJ11183); Anti -FGD6 (KIAA1362; anti-FGD6 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human FGD6.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVVEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPWKHFWFVIKNKVLYTYAASEVRSEI

• Applicable Applications for anti-FGD6 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human FGD6, aa1-376 (AAH13319.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of FGD6 expression in transfected 293T cell line by FGD6 polyclonal antibody. Lane 1: FGD6 transfected lysate (41.36kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-FGD6 antibody

May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape.

Product Categories/Family for anti-FGD6 antibody

Antibodies; Abs to G Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 211825997
• NCBI GeneID: 55785
• UniProt Accession #: Q6ZV73; Q6ZR53; Q7Z2Z7; Q96D44; Q9NUR8; Q9P2I5
• Molecular Weight: 160,816 Da
• NCBI Official Full Name: FGD6 protein
• NCBI Official Synonym Full Names: FYVE, RhoGEF and PH domain containing 6
• NCBI Official Symbol: FGD6
• NCBI Official Synonym Symbols: ZFYVE24
• NCBI Protein Information: FYVE, RhoGEF and PH domain-containing protein 6; zinc finger FYVE domain-containing protein 24
• UniProt Protein Name: FYVE, RhoGEF and PH domain-containing protein 6
• Protein Family: FYVE, RhoGEF and PH domain-containing protein
• UniProt Gene Name: FGD6
• UniProt Synonym Gene Names: KIAA1362; ZFYVE24
• UniProt Entry Name: FGD6_HUMAN

Uniprot Description

FGD6: May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs, Rac/Rho; GEFs

Chromosomal Location of Human Ortholog: 12q22

Cellular Component: ruffle; Golgi apparatus; cytoskeleton; lamellipodium; cytoplasm

Molecular Function: small GTPase binding; Rho guanyl-nucleotide exchange factor activity; metal ion binding; guanyl-nucleotide exchange factor activity

Biological Process: regulation of cell shape; filopodium formation; cytoskeleton organization and biogenesis; actin cytoskeleton organization and biogenesis; positive regulation of GTPase activity