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Western Blot (WB) (C14orf106 polyclonal antibody. Western Blot analysis of C14orf106 expression in human spleen.)

Mouse anti-Human MIS18BP1 Polyclonal Antibody | anti-MIS18BP1 antibody

MIS18BP1 (C14orf106, Mis18-binding Protein 1, Kinetochore-associated Protein KNL-2 Homolog, HsKNL-2, P243, KIAA1903, FLJ11186, HSA242977)

Gene Names
MIS18BP1; KNL2; M18BP1; C14orf106; HSA242977
Reactivity
Human
Applications
Western Blot, Immunofluorescence
Purity
Purified by Protein A affinity chromatography.
Synonyms
MIS18BP1; Polyclonal Antibody; MIS18BP1 (C14orf106; Mis18-binding Protein 1; Kinetochore-associated Protein KNL-2 Homolog; HsKNL-2; P243; KIAA1903; FLJ11186; HSA242977); Anti -MIS18BP1 (C14orf106; anti-MIS18BP1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human C14orf106.
Purity/Purification
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4.
Sequence
MIATPLKHSRIYLPPEASSQRRNLPMDAIFFDSIPSGTLTPVKDLVKYQNSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGLKNKANYESPGKIFLRMKEKVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKKKLQHTYLCEEKENNKSFQSDDSSLRASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYELPTLNQEQENFLAVEARNKTLTRAQLAKQIFHSKESIVATTKSKKDTFVLESVDSADEQFQNTNAETLSTNCIPIKNGSLLMVSDSERTTEGTS
Applicable Applications for anti-MIS18BP1 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml
Grade
Affinity Purified
Immunogen
Full-length recombinant protein corresponding to aa1-314 fromhuman MIS18BP1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(C14orf106 polyclonal antibody. Western Blot analysis of C14orf106 expression in human spleen.)

Western Blot (WB) (C14orf106 polyclonal antibody. Western Blot analysis of C14orf106 expression in human spleen.)

Western Blot (WB)

(Western Blot analysis of C14orf106 expression in transfected 293T cell line by C14orf106 polyclonal antibody. Lane 1: C14orf106 transfected lysate (34.54kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of C14orf106 expression in transfected 293T cell line by C14orf106 polyclonal antibody. Lane 1: C14orf106 transfected lysate (34.54kD). Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence of purified antibody to C14orf106 on HeLa cell. [antibody concentration 10ug/ml].)

Immunofluorescence (IF) (Immunofluorescence of purified antibody to C14orf106 on HeLa cell. [antibody concentration 10ug/ml].)
Related Product Information for anti-MIS18BP1 antibody
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Product Categories/Family for anti-MIS18BP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Mis18-binding protein 1
NCBI Official Synonym Full Names
MIS18 binding protein 1
NCBI Official Symbol
MIS18BP1
NCBI Official Synonym Symbols
KNL2; M18BP1; C14orf106; HSA242977
NCBI Protein Information
mis18-binding protein 1; P243; hsKNL-2; kinetochore null 2 homolog; kinetochore-associated protein KNL-2 homolog; putative protein p243 which interacts with transcription factor Sp1
UniProt Protein Name
Mis18-binding protein 1
Protein Family
UniProt Gene Name
MIS18BP1
UniProt Synonym Gene Names
C14orf106; KIAA1903; KNL2; M18BP1; HsKNL-2
UniProt Entry Name
M18BP_HUMAN

Uniprot Description

KNL2: a potential transcriptional regulatory protein. Interacts with SP1. Two alternatively-spliced isoforms have been described.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 14q21.2

Cellular Component: nucleoplasm; chromosome, pericentric region

Molecular Function: protein binding; DNA binding; chromatin binding

Biological Process: nucleosome assembly; mitosis; DNA replication-independent nucleosome assembly at centromere; cell division

Research Articles on MIS18BP1

Similar Products

Product Notes

The MIS18BP1 mis18bp1 (Catalog #AAA6007437) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MIS18BP1 (C14orf106, Mis18-binding Protein 1, Kinetochore-associated Protein KNL-2 Homolog, HsKNL-2, P243, KIAA1903, FLJ11186, HSA242977) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MIS18BP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Suitable for use in Immunofluorescence and Western Blot. Dilution: Immunofluorescence: 10ug/ml. Researchers should empirically determine the suitability of the MIS18BP1 mis18bp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MIATPLKHSR IYLPPEASSQ RRNLPMDAIF FDSIPSGTLT PVKDLVKYQN SSLKLNDHKK NQFLKMTTFN NKNIFQSTML TEATTSNSSL DISAIKPNKD GLKNKANYES PGKIFLRMKE KVLRDKQEQP SRNSSLLEPQ KSGNNETFTP NRVEKKKLQH TYLCEEKENN KSFQSDDSSL RASVQGVPLE SSNNDIFLPV KQKIQCQQEK KAPLHNLTYE LPTLNQEQEN FLAVEARNKT LTRAQLAKQI FHSKESIVAT TKSKKDTFVL ESVDSADEQF QNTNAETLST NCIPIKNGSL LMVSDSERTT EGTS. It is sometimes possible for the material contained within the vial of "MIS18BP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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