Rabbit anti-Human SESTD1 Polyclonal Antibody | anti-SESTD1 antibody

SESTD1, CT (SEC14 Domain and Spectrin Repeat-containing Protein 1, Huntingtin-interacting Protein-like Protein, Protein Solo, SOLO)

Cat. Num. AAA6006280

• Gene Names: SESTD1; SOLO
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: SESTD1; Polyclonal Antibody; CT (SEC14 Domain and Spectrin Repeat-containing Protein 1; Huntingtin-interacting Protein-like Protein; Protein Solo; SOLO); Anti -SESTD1; anti-SESTD1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human SESTD1. Species sequence homology: mouse and rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.02% sodium azide.

• Applicable Applications for anti-SESTD1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: Western Blot: 1-2ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
• Immunogen: Synthetic peptide corresponding to 15aa from human SESTD1 at C-terminus.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))

Related Product Information for anti-SESTD1 antibody

May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.

Product Categories/Family for anti-SESTD1 antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 188528641
• NCBI GeneID: 91404
• NCBI Accession #: NP_835224.3
• NCBI GenBank Nucleotide #: NM_178123.4
• UniProt Accession #: Q86VW0; Q53R38; Q53SP3; Q5GM69; Q8N6M1; Q96LQ2
• Molecular Weight: 79,348 Da
• NCBI Official Full Name: SEC14 domain and spectrin repeat-containing protein 1
• NCBI Official Synonym Full Names: SEC14 and spectrin domains 1
• NCBI Official Symbol: SESTD1
• NCBI Official Synonym Symbols: SOLO
• NCBI Protein Information: SEC14 domain and spectrin repeat-containing protein 1; protein Solo; huntingtin-interacting protein-like protein
• UniProt Protein Name: SEC14 domain and spectrin repeat-containing protein 1
• Protein Family: SEC14 domain and spectrin repeat-containing protein
• UniProt Gene Name: SESTD1
• UniProt Synonym Gene Names: SOLO
• UniProt Entry Name: SESD1_HUMAN

Uniprot Description

SESTD1: May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1. Belongs to the SOLO family.

Chromosomal Location of Human Ortholog: 2q31.2

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; protein binding; phosphatidylserine binding; phosphatidylinositol-5-phosphate binding; phosphatidylcholine binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol 3-phosphate binding; phosphatidylinositol binding