Chemical Structure
R243, inhibitor
R243
Purity
0.9786
Synonyms
R243; R 243; R-243; inhibitor
Purity/Purification
0.9786
Form/Format
Solid
Solubility
DMSO: 125mg/mL (349.71mM)
Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
C1C2CC3CC1CC(C2)(C3)OCCN4CC5=CC6=C(C=C5OC4)OCO6
Formula
C21H27NO4
CAS Number
688352-84-3
Preparation and Storage
Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).
Chemical Structure
Chemical Structure
Related Product Information for R243, inhibitor
R243 is CCR8 signaling and chemotaxis inhibitor.
Product Categories/Family for R243, inhibitor
References
Berenguer J, Lagerweij T, Zhao XW, et al. Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8. J Extracell Vesicles. 2018 Mar 13;7(1):1446660. doi: 10.1080/20013078.2018.1446660. eCollection 2018. PubMed PMID: 29696074.
Huber DA, Schreihofer AM. Exaggerated sympathoexcitatory reflexes develop with changes in the rostral ventrolateral medulla in obese Zucker rats. Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R243-53. doi: 10.1152/ajpregu.00085.2016. Epub 2016 Jun 8. PubMed PMID: 27280427.
Wan H, Otsuka Y, Gao ZQ, Wei Y, Chen Z, Masuda M, Yonesaki T, Zhang H, Dong YH. Structural insights into the inhibition mechanism of bacterial toxin LsoA by bacteriophage antitoxin Dmd. Mol Microbiol. 2016 Sep;101(5):757-69. doi: 10.1111/mmi.13420. Epub 2016 Jun 2. PubMed PMID: 27169810.
Richards MB, Soares P, Torroni A. Palaeogenomics: Mitogenomes and Migrations in Europe's Past. Curr Biol. 2016 Mar 21;26(6):R243-6. doi: 10.1016/j.cub.2016.01.044. PubMed PMID: 27003890.
Huber DA, Schreihofer AM. Exaggerated sympathoexcitatory reflexes develop with changes in the rostral ventrolateral medulla in obese Zucker rats. Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R243-53. doi: 10.1152/ajpregu.00085.2016. Epub 2016 Jun 8. PubMed PMID: 27280427.
Wan H, Otsuka Y, Gao ZQ, Wei Y, Chen Z, Masuda M, Yonesaki T, Zhang H, Dong YH. Structural insights into the inhibition mechanism of bacterial toxin LsoA by bacteriophage antitoxin Dmd. Mol Microbiol. 2016 Sep;101(5):757-69. doi: 10.1111/mmi.13420. Epub 2016 Jun 2. PubMed PMID: 27169810.
Richards MB, Soares P, Torroni A. Palaeogenomics: Mitogenomes and Migrations in Europe's Past. Curr Biol. 2016 Mar 21;26(6):R243-6. doi: 10.1016/j.cub.2016.01.044. PubMed PMID: 27003890.
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Product Notes
The R243 (Catalog #AAA5764851) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "R243, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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