Argipressin, Inhibitor
Argipressin
Purity
98.00%
Synonyms
Argipressin; Vasopressin; Arg8-vasopressin; AVP; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
H2O: 100mg/mL (92.23mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C46H65N15O12S2
SMILES
CC(=O)O.N=C(N)NCCCC(NC(=O)C1CCCN1C(=O)C1CSSCC(N)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(Cc2ccccc2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
CAS Number
113-79-1
Target & IC50
Others
In Vitro
In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600ng.
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Argipressin, inhibitor
Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.
References
Byron K L. Vasopressin Stimulates Ca2+ Spiking Activity in A7r5 Vascular Smooth Muscle Cells via Activation of Phospholipase A2[J]. Circulation Research, 1996, 78(5):813-20.
Byron K L. Vasopressin Stimulates Ca2+ Spiking Activity in A7r5 Vascular Smooth Muscle Cells via Activation of Phospholipase A2[J]. Circulation Research, 1996, 78(5):813-20.
Jiang N C, Gao L, Chen C, et al. Effects of argipressin injected into medial amygdaloid body on blood pressure and heart rate in rats[J]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, 14(2):118-120.
Jiang N C, Gao L, Chen C, et al. Effects of argipressin injected into medial amygdaloid body on blood pressure and heart rate in rats[J]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, 14(2):118-120.
Keun Suk Park, et al. Role of vasopressin in current anesthetic practice. Korean J Anesthesiol. 2017 Jun; 70(3): 245-257.
Byron K L. Vasopressin Stimulates Ca2+ Spiking Activity in A7r5 Vascular Smooth Muscle Cells via Activation of Phospholipase A2[J]. Circulation Research, 1996, 78(5):813-20.
Jiang N C, Gao L, Chen C, et al. Effects of argipressin injected into medial amygdaloid body on blood pressure and heart rate in rats[J]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, 14(2):118-120.
Jiang N C, Gao L, Chen C, et al. Effects of argipressin injected into medial amygdaloid body on blood pressure and heart rate in rats[J]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, 14(2):118-120.
Keun Suk Park, et al. Role of vasopressin in current anesthetic practice. Korean J Anesthesiol. 2017 Jun; 70(3): 245-257.
Similar Products
Product Notes
The Argipressin (Catalog #AAA5758330) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Argipressin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
