Structure
Hypromellose, Inhibitor
Hypromellose
Purity
98.00%
Synonyms
Hypromellose; (Hydroxypropyl)methyl cellulose; HPMC; Celacol HPM 5000; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: 25mg/mL Need ultrasonic
H2O: 10mg/mL Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
H2O: 10mg/mL Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
[R]O[C@@H]1[C@H](O[R])[C@@H](O[R])[C@H](O[C@H]2[C@H](O[R])[C@@H](O[R])[C@H](O[R])[C@@H](CO[R])O2)[C@@H](CO[R])O1.CO.CC(O)CO.[n].[x]
CAS Number
9004-65-3
Target & IC50
Others
In Vitro
Hypromellose (hydroxypropylmethylcellulose) has been used in sustained-release pharmaceutical products for many years. When used in matrix tablets, these polymers hydrate on contact with water to produce a viscous gel barrier within and surrounding the tablet. The properties of hypromellose that affect the rate of drug release include the rate of diffusion of water into the dry polymer, the rate of hypromellose hydration and gel formation, the viscosity of the hydrated hypromellose and rate of hypromellose gel erosion.Hypromellose provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect.
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for Hypromellose, inhibitor
Hypromellose is a water-soluble hydrophilic, non-ionic cellulose ether.
References
Li CL, et al. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46.
Li CL, et al. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46.
Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing.
Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing.
Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Cornea. 2015 Feb;34(2):188-92.
Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Cornea. 2015 Feb;34(2):188-92.
Ban SJ, et al. Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet. Int J Mol Sci. 2012;13(3):3738-50.
Ban SJ, et al. Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet. Int J Mol Sci. 2012;13(3):3738-50.
Li CL, et al. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46.
Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing.
Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing.
Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Cornea. 2015 Feb;34(2):188-92.
Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Cornea. 2015 Feb;34(2):188-92.
Ban SJ, et al. Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet. Int J Mol Sci. 2012;13(3):3738-50.
Ban SJ, et al. Antihyperglycemic and antioxidative effects of Hydroxyethyl Methylcellulose (HEMC) and Hydroxypropyl Methylcellulose (HPMC) in mice fed with a high fat diet. Int J Mol Sci. 2012;13(3):3738-50.
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Product Notes
The Hypromellose (Catalog #AAA5756029) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Hypromellose, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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