Rabbit RPS5 Polyclonal Antibody | anti-RPS5 antibody

RPS5 Polyclonal Antibody

Cat. Num. AAA3011873

• Gene Names: RPS5; S5
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: RPS5; Polyclonal Antibody; RPS5 Polyclonal Antibody; 40S ribosomal protein S5; anti-RPS5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RPS5 polyclonal antibody detects endogenous levels of RPS5 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 204

• Applicable Applications for anti-RPS5 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000; IF: 1:50-1:200
• Immunogen: Recombinant full length Human RPS5.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using RPS5 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U20S cell using RPS5 antibody. Blue: DAPI for nuclear staining.)

Related Product Information for anti-RPS5 antibody

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

NCBI and Uniprot Product Information

• NCBI GI #: 13904870
• NCBI GeneID: 6193
• NCBI Accession #: NP_001000.2
• NCBI GenBank Nucleotide #: NP_001000.2
• UniProt Accession #: P46782
• Molecular Weight: ~ 23kDa
• NCBI Official Full Name: 40S ribosomal protein S5
• NCBI Official Synonym Full Names: ribosomal protein S5
• NCBI Official Symbol: RPS5
• NCBI Official Synonym Symbols: S5
• NCBI Protein Information: 40S ribosomal protein S5
• UniProt Protein Name: 40S ribosomal protein S5
• Protein Family: 30S ribosomal protein
• UniProt Gene Name: RPS5
• UniProt Entry Name: RS5_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Uniprot Description

RPS5: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Protein type: RNA-binding; Ribosomal; Translation

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: focal adhesion; membrane; ribonucleoprotein complex; cytosol

Molecular Function: mRNA binding; structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; translation; viral reproduction; regulation of translational fidelity; translational initiation; mRNA catabolic process, nonsense-mediated decay; viral transcription; gene expression; translational termination; viral infectious cycle